D
Dhaneswar Prusty
Researcher at Central University of Rajasthan
Publications - 20
Citations - 452
Dhaneswar Prusty is an academic researcher from Central University of Rajasthan. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 10, co-authored 14 publications receiving 328 citations. Previous affiliations of Dhaneswar Prusty include Jawaharlal Nehru University & McMaster University.
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Journal ArticleDOI
The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasite.
Johanna Wetzel,Susann Herrmann,Lakshmipuram S. Swapna,Dhaneswar Prusty,Arun T. John Peter,Maya Kono,Sidharth Saini,Srinivas Nellimarla,Tatianna Wai Ying Wong,Louisa Wilcke,Louisa Wilcke,Olivia Ramsay,Ana Cabrera,Laura Biller,Dorothee Heincke,Dorothee Heincke,Karen L. Mossman,Tobias Spielmann,Christian Ungermann,John Parkinson,Tim W. Gilberger,Tim W. Gilberger +21 more
TL;DR: Systematic phylogenetic analysis of the alveolate PAT family reveals PfDHHC1 to be a member of a highly conserved, apicomplexan-specific clade of PATs, and this enzyme has an identical distribution like two dual-acylated, IMC-localized proteins.
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High throughput virtual screening reveals SARS-CoV-2 multi-target binding natural compounds to lead instant therapy for COVID-19 treatment.
TL;DR: Three novel multi-target natural compounds were predicted to subdue the activity of three/more major drug targets simultaneously and are proposed as excellent lead candidates for the development of therapeutic drugs against SARS-CoV-2.
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Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.
Dhaneswar Prusty,Parul Mehra,Sandeep Srivastava,Amol V. Shivange,Ashish Gupta,Nilanjan Roy,Suman Kumar Dhar +6 more
TL;DR: The presence of PfSir2 in the parasite at the protein level by specific antibodies is reported and the possibility of using an inexpensive agent like nicotinamide as an antimalarial in combination with other antiparasitic drugs is raised.
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Strategic Development of a Next-Generation Multi-Epitope Vaccine To Prevent Nipah Virus Zoonotic Infection
TL;DR: The next-generation approach will provide a new vision for the development of a high immunogenic vaccine against the NiV and generate the humoral as well as cell-mediated immunity.
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The apicomplexan inner membrane complex.
TL;DR: A plethora of proteins and their varying evolutionary origin underlines the versatility of the IMC as a result of the adaption to a parasitic lifestyle.