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Diego A. Pizzagalli
Researcher at Harvard University
Publications - 393
Citations - 27176
Diego A. Pizzagalli is an academic researcher from Harvard University. The author has contributed to research in topics: Anhedonia & Medicine. The author has an hindex of 74, co-authored 327 publications receiving 21846 citations. Previous affiliations of Diego A. Pizzagalli include Stanford University & McLean Hospital.
Papers
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Journal ArticleDOI
Large-Scale Network Dysfunction in Major Depressive Disorder: A Meta-analysis of Resting-State Functional Connectivity.
TL;DR: A meta-analysis of rsFC studies provides an empirical foundation for a neurocognitive model in which network dysfunction underlies core cognitive and affective abnormalities in depression.
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Depression: perspectives from affective neuroscience.
TL;DR: A model of the ways in which affect can become disordered in depression is constructed and proposals for the specific types of processing abnormalities that result from dysfunctions in different parts of this circuitry are offered.
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Effects of early life stress on cognitive and affective function: an integrated review of human literature.
Pia Pechtel,Diego A. Pizzagalli +1 more
TL;DR: Higher-order, complex cognitive and affective functions associated with brain regions undergoing protracted postnatal development are particularly vulnerable to the deleterious effects of ELS, and the amygdala is particularly sensitive to early ELS.
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Reduced Caudate and Nucleus Accumbens Response to Rewards in Unmedicated Individuals With Major Depressive Disorder
Diego A. Pizzagalli,Avram J. Holmes,Daniel G. Dillon,B.A. Elena L. Goetz,B.A. Jeffrey L. Birk,A.M. Ryan Bogdan,Darin D. Dougherty,Dan V. Iosifescu,Scott L. Rauch,Maurizio Fava +9 more
TL;DR: Results suggest that basal ganglia dysfunction in major depression may affect the consummatory phase of reward processing, and morphometric results suggest that anhedonia in major Depression is related to caudate volume.
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Depression, stress, and anhedonia: toward a synthesis and integrated model.
TL;DR: A heuristic model is presented postulating that anhedonia arises from dysfunctional interactions between stress and brain reward systems, and a synthesis of these four literatures is provided.