Diego A. Pizzagalli

TL;DR: In this article , the authors examined whether baseline brain structure was prospectively related to the trajectory of the p factor and specific forms of psychopathology over 2 years in 9,220 preadolescents (aged 9-10 at baseline) from the Adolescent Brain Cognitive Development Study.

TL;DR: A rat flanker task with electrophysiological recordings based on reverse-translated protocols used in human electroencephalogram (EEG) studies of cognitive control and rodent touchscreen-based cognitive testing is developed to verify the feasibility and encourage future use of this integrated approach in therapeutics development.

TL;DR: Compared to the non-PTSD control group, veterans with PTSD showed significantly greater punishment-based learning and greater change in response bias for responding toward a less frequently punished stimulus across blocks.

TL;DR: Examination of stress-induced changes in mPFC glutamate using magnetic resonance spectroscopy in four human samples varying in perceived stress exposure provides novel evidence for glutamatergic adaptation to stress inmPFC that is significantly disrupted in MDD.