Diego A. Pizzagalli

TL;DR: Findings indicate that frontal lobe structural alterations in the first week of treatment may be associated with long-term treatment efficacy, and may help to elucidate the specific neural targets of SSRIs.

TL;DR: Results extend prior IAT research by documenting the presence of a reduced tendency to associate the self with happiness in a sample at increased risk for depression by examining automatic associations between the self and mood state and between the future and moodState.

TL;DR: It is suggested that measures of reward-related mesolimbic dopamine function may hold promise for identifying depressed individuals likely to respond favourably to dopaminergic pharmacotherapy.

TL;DR: In this paper, the authors show that 8 weeks of treatment with a kappa-opioid receptor (KOR) antagonist resulted in significantly higher reward-related activation in one of the core hubs of the brain reward system (the ventral striatum), better reward learning in the Probabilistic Reward Task (PRT), and lower anhedonic symptoms.

TL;DR: Healthy adolescents endorsed, recalled, and recognized more positive and fewer negative words at each assessment, and the internal reliability of ERPs were robust at each time point, suggesting that the SRET is a reliable behavioral and neural probe of self-referential processing.