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Dominique Baas
Researcher at Claude Bernard University Lyon 1
Publications - 23
Citations - 1450
Dominique Baas is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Cilium & Ciliogenesis. The author has an hindex of 16, co-authored 22 publications receiving 1302 citations. Previous affiliations of Dominique Baas include University of Lyon & Centre national de la recherche scientifique.
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Journal ArticleDOI
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
Valérie Risson,Laetitia Mazelin,Mila Roceri,Hervé Sanchez,Vincent Moncollin,Claudine Corneloup,Hélène Richard-Bulteau,Alban Vignaud,Dominique Baas,Aurelia Defour,Damien Freyssenet,Jean-François Tanti,Jean-François Tanti,Yannick Le-Marchand-Brustel,Yannick Le-Marchand-Brustel,Bernard Ferrier,Agnès Conjard-Duplany,Klaas Romanino,S. Bauche,Daniel Hantaï,Matthias Mueller,Sara C. Kozma,George Thomas,Markus A. Rüegg,Arnaud Ferry,Mario Pende,Xavier Bigard,Nathalie Koulmann,Laurent Schaeffer,Yann-Gaël Gangloff +29 more
TL;DR: mTor, acting mainly via mTORC1, controls dystrophin transcription in a raptor- and rictor-independent mechanism.
Journal ArticleDOI
The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification
Elsa Bonnafé,M. Touka,Aouatef Ait-Lounis,Dominique Baas,Emmanuèle Barras,Catherine Ucla,A. Moreau,Frédéric Flamant,Raphaëlle Dubruille,Pierre Couble,J. Collignon,Bénédicte Durand,Walter Reith +12 more
TL;DR: It is shown that RFX3 regulates the expression of D2lic, the mouse orthologue of a Caenorhabditis elegans gene that is implicated in intraflagellar transport, a process required for the assembly and maintenance of cilia.
Journal ArticleDOI
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles
Sandrine Alais,Sabrina Simoes,Dominique Baas,Dominique Baas,Sylvain Lehmann,Graça Raposo,Jean-Luc Darlix,Jean-Luc Darlix,Pascal Leblanc,Pascal Leblanc +9 more
TL;DR: In this paper, the authors found that both prion proteins and scrapie infectivity are mainly associated with exosome-like structures that contain viral envelope glycoprotein and nucleic acids, such as RNAs.
Journal ArticleDOI
A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells.
Dominique Baas,A. Meiniel,Carine Benadiba,Elsa Bonnafé,O. Meiniel,Walter Reith,Bénédicte Durand +6 more
TL;DR: It is shown here that Rfx3‐deficient mice suffer from hydrocephalus without stenosis of the aqueduct of Sylvius, demonstrating that RFX3 is necessary for ciliated ependymal cell differentiation in the mouse.
Journal ArticleDOI
Novel Function of the Ciliogenic Transcription Factor RFX3 in Development of the Endocrine Pancreas
Aouatef Ait-Lounis,Dominique Baas,Emmanuèle Barras,Carine Benadiba,Anne Charollais,Rachel Nlend Nlend,Delphine Liègeois,Paolo Meda,Bénédicte Durand,Walter Reith +9 more
TL;DR: It is shown that mouse RFX3 is expressed in developing and mature pancreatic endocrine cells during embryogenesis and in adults, and that the presence of primary cilia on islet cells may play a key role in this process.