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Damien Freyssenet

Researcher at University of Lyon

Publications -  69
Citations -  9021

Damien Freyssenet is an academic researcher from University of Lyon. The author has contributed to research in topics: Skeletal muscle & Mitochondrial biogenesis. The author has an hindex of 34, co-authored 66 publications receiving 8209 citations. Previous affiliations of Damien Freyssenet include Jean Monnet University & Lyon College.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Down-Regulation of Akt/Mammalian Target of Rapamycin Signaling Pathway in Response to Myostatin Overexpression in Skeletal Muscle

TL;DR: The data support the conclusion that Akt/mTOR signaling is a key target that accounts for myostatin function during muscle atrophy, uncovering a novel role for hisostatin in protein metabolism and more specifically in the regulation of translation in skeletal muscle.
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Molecular adaptations of neuromuscular disease-associated proteins in response to eccentric exercise in human skeletal muscle

TL;DR: The results suggest that the differential expression of calpain 2 and 3 mRNA levels may be important in the process of exercise‐induced muscle damage, whereas expression of α‐sarcoglycan, desmin, αB‐crystallin and Hsp27 may be essentially involved in the subsequent remodelling of myofibrillar structure.
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Mitochondrial biogenesis during skeletal muscle regeneration

TL;DR: The results suggest that mitochondrial biogenesis may be an important regulatory event during muscle regeneration, and transcriptional activation by PGC-1 and mtTFA may be one of the mechanisms regulating mitochondrialBiogenesis in regenerating skeletal muscle.