D
Donald W. Paty
Researcher at University of British Columbia
Publications - 162
Citations - 31395
Donald W. Paty is an academic researcher from University of British Columbia. The author has contributed to research in topics: Multiple sclerosis & Magnetic resonance imaging. The author has an hindex of 60, co-authored 162 publications receiving 30430 citations. Previous affiliations of Donald W. Paty include UBC Hospital & Vancouver General Hospital.
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Journal ArticleDOI
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.
Charles M. Poser,Donald W. Paty,Labe C. Scheinberg,W I McDonald,F A Davis,George C. Ebers,Kenneth P. Johnson,William A. Sibley,Donald H. Silberberg,Wallace W. Tourtellotte +9 more
TL;DR: Today there is a need for more exact criteria than existed earlier in order to conduct therapeutic trials in multicenter programs, to compare epidemiological surveys, to evaluate new diagnostic procedures, and to estimate the activity of the disease process in MS.
Journal ArticleDOI
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis
W. Ian McDonald,A Compston,Gilles Edan,Donald E. Goodkin,Hans-Peter Hartung,Fred D. Lublin,Henry F. McFarland,Donald W. Paty,Chris H. Polman,Stephen C. Reingold,Magnhild Sandberg-Wollheim,William A. Sibley,Alan J. Thompson,Stanley van den Noort,Brian Y. Weinshenker,Jerry S. Wolinsky +15 more
TL;DR: The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including “monosymptomatic” disease suggestive of MS, disease with a typical relapsing‐remitting course, and disease with insidious progression, without clear attacks and remissions.
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In vivo visualization of myelin water in brain by magnetic resonance
TL;DR: The intrinsic difference in magnetic resonance spin‐spin relaxation time, T2, between water associated with myelin sheaths and water in other central nervous system tissue is exploited to measure myelin water content within any region of an image or to generate indirectly a myelin map of the brain.
Journal Article
TNF neutralization in MS - Results of a randomized, placebo-controlled multicenter study
Arnason Bgw.,G Jacobs,M Hanlon,B H Clay,Noronha Abc.,A Auty,B Davis,Avindra Nath,Jean-Pierre Bouchard,C Belanger,F Gosselin,Manon Thibault,Pierre Duquette,P Bourgoin,Rebecca M. DuBois,M. Girard,George C. Ebers,Rice Gpa.,Margaret K. Vandervoort,Gordon S. Francis,L Duncan,Yves Lapierre,M. S. Freedman,S N Christie,Hyman Rabinovitch,David G. Patry,W F Murphy,S Peters,S D McGuiness,T J Murray,Virender Bhan,Charles Maxner,R. A. Van Dorpe,J J Oger,J. Nelson,W. Morrison,N Bogle,S Beall,G Vorobeychick,A V Hiltbrunner,J Bock,W Lesslauer,Li Dkb.,Donald W. Paty,Guojun Zhao,Grp Lmss.,Grp Ubcmsmria. +46 more
TL;DR: Lenercept failed to be beneficial, but insight into the role of TNF in MS exacerbations was gained.
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In vivo measurement of T2 distributions and water contents in normal human brain
TL;DR: In this paper, T2 relaxation decay curves were acquired from five white and six gray-matter brain structures outlined in 12 normal volunteers, and the water contents of white and gray matter were 0.71 and 0.83 g/ml, respectively.