D
Dong-Ju You
Researcher at Osaka University
Publications - 2
Citations - 247
Dong-Ju You is an academic researcher from Osaka University. The author has contributed to research in topics: Semaphorin & Integrin alpha M. The author has an hindex of 2, co-authored 2 publications receiving 208 citations.
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Journal ArticleDOI
Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β.
Tadaomi Kawashima,Akemi Kosaka,Huimin Yan,Zijin Guo,Ryosuke Uchiyama,Ryutaro Fukui,Daisuke Kaneko,Yutaro Kumagai,Dong-Ju You,Joaquim Carreras,Satoshi Uematsu,Myoung Ho Jang,Myoung Ho Jang,Osamu Takeuchi,Osamu Takeuchi,Tsuneyasu Kaisho,Shizuo Akira,Kensuke Miyake,Hiroko Tsutsui,Takashi Saito,Ikuko Nishimura,Noriko M. Tsuji +21 more
TL;DR: It is suggested that dsRNA in commensal bacteria contributes to anti-inflammatory and protective immune responses and is identified as a discriminatory sensor to small intestinal commensals by using Toll-like receptor 3.
Journal ArticleDOI
Intestinal Epithelial Cell-Derived Semaphorin 7A Negatively Regulates Development of Colitis via αvβ1 Integrin
Sujin Kang,Tatsusada Okuno,Noriko Takegahara,Hyota Takamatsu,Satoshi Nojima,Tetsuya Kimura,Yuji Yoshida,Daisuke Ito,Saori Ohmae,Dong-Ju You,Toshihiko Toyofuku,Myoung Ho Jang,Myoung Ho Jang,Atsushi Kumanogoh +13 more
TL;DR: Findings indicate that Sema7A plays crucial roles in suppressing intestinal inflammation through αvβ1 integrin, but also provide a novel mode of IL-10 induction via interactions between IECs and Mφs.