D
Doris Rassl
Researcher at Papworth Hospital
Publications - 72
Citations - 3703
Doris Rassl is an academic researcher from Papworth Hospital. The author has contributed to research in topics: Lung cancer & Lung. The author has an hindex of 21, co-authored 64 publications receiving 2861 citations. Previous affiliations of Doris Rassl include University of Cambridge.
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Journal ArticleDOI
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
Elza C de Bruin,Nicholas McGranahan,Nicholas McGranahan,Richard Mitter,Max Salm,David C. Wedge,Lucy R. Yates,Lucy R. Yates,Mariam Jamal-Hanjani,Seema Shafi,Nirupa Murugaesu,Andrew Rowan,Eva Grönroos,Madiha A. Muhammad,Stuart Horswell,Marco Gerlinger,Ignacio Varela,David T. Jones,John Marshall,Thierry Voet,Thierry Voet,Peter Van Loo,Peter Van Loo,Doris Rassl,Robert C. Rintoul,Sam M. Janes,Siow Ming Lee,Martin Forster,Tanya Ahmad,David Lawrence,Mary Falzon,Arrigo Capitanio,Timothy T. Harkins,Clarence C. Lee,Warren Tom,Enock Teefe,Shann-Ching Chen,Sharmin Begum,Adam Rabinowitz,Benjamin Phillimore,Bradley Spencer-Dene,Gordon Stamp,Zoltan Szallasi,Zoltan Szallasi,Nik Matthews,Aengus Stewart,Peter J. Campbell,Charles Swanton,Charles Swanton +48 more
TL;DR: 25 spatially distinct regions from seven operable NSCLCs were sequenced and found evidence of branched evolution, with driver mutations arising before and after subclonal diversification, and pronounced intratumor heterogeneity in copy number alterations, translocations, and mutations associated with APOBEC cytidine deaminase activity.
Journal ArticleDOI
The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation
Gerald J. Berry,Margaret Burke,Claus B. Andersen,Patrick Bruneval,Marny Fedrigo,Michael C. Fishbein,Martin Goddard,Elizabeth H. Hammond,Ornella Leone,Charles C. Marboe,Dylan V. Miller,Desley Neil,Doris Rassl,Monica P. Revelo,Alexandra Rice,E. Rene Rodriguez,Susan Stewart,Carmela D. Tan,Gayle L. Winters,Lori J. West,Mandeep R. Mehra,Annalisa Angelini +21 more
TL;DR: The consensus findings from a series of meetings held between 2010-2012 to develop a Working Formulation for the pathologic diagnosis, grading, and reporting of cardiac antibody-mediated rejection are reported.
Journal ArticleDOI
Pleuroparenchymal fibroelastosis: a spectrum of histopathological and imaging phenotypes.
Taryn L. Reddy,Masaki Tominaga,David M. Hansell,Jan H. von der Thüsen,Doris Rassl,Helen Parfrey,Suzy Guy,Orion M. Twentyman,Alexandra Rice,Toby M. Maher,Elisabetta A. Renzoni,Athol U. Wells,Andrew G. Nicholson +12 more
TL;DR: PPFE is a distinct clinicopathological entity, with clinical data suggesting a link to recurrent pulmonary infection and genetic and autoimmune mechanisms may also contribute to the development of these changes.
Journal ArticleDOI
Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non-small cell lung cancer: a multicenter study of 774 patients.
Neal Navani,James Brown,Matthew Nankivell,Ian Woolhouse,Richard Harrison,Vandana Jeebun,Mohammed Munavvar,Benjamin J. Ng,Doris Rassl,Mary Falzon,Gabrijela Kocjan,Robert C. Rintoul,Andrew G. Nicholson,Sam M. Janes +13 more
TL;DR: In this paper, a large multicenter pragmatic study was conducted to determine whether cytology specimens obtained from EBUS-TBNA in routine practice are suitable for phenotyping and genotyping of non-small cell lung cancer.
Journal ArticleDOI
Extensive heterogeneity in somatic mutation and selection in the human bladder
Andrew R. J. Lawson,Federico Abascal,Tim H. H. Coorens,Yvette Hooks,Laura O’Neill,Calli Latimer,Keiran Raine,Mathijs A. Sanders,Mathijs A. Sanders,Anne Y. Warren,Krishnaa T. Mahbubani,Bethany Bareham,Tim Butler,Luke M. R. Harvey,Alex Cagan,Andrew Menzies,Luiza Moore,Luiza Moore,Alexandra Colquhoun,William Turner,Benjamin Thomas,Benjamin Thomas,Vincent Gnanapragasam,Nicholas Williams,Doris Rassl,Harald Vöhringer,Sonia Zumalave,Jyoti Nangalia,Jose M. C. Tubio,Jose M. C. Tubio,Moritz Gerstung,Kourosh Saeb-Parsy,Michael R. Stratton,Peter J. Campbell,Peter J. Campbell,Thomas J. Mitchell,Thomas J. Mitchell,Inigo Martincorena +37 more
TL;DR: A rich landscape of mutational processes and selection in normal urothelium with large heterogeneity across clones and individuals is revealed, which suggests differential exposure to mutagens in the urine.