D
Douglas Wilson
Researcher at Edendale Hospital
Publications - 50
Citations - 2598
Douglas Wilson is an academic researcher from Edendale Hospital. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 19, co-authored 46 publications receiving 2257 citations. Previous affiliations of Douglas Wilson include University of Cape Town & University of KwaZulu-Natal.
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Journal ArticleDOI
Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study.
TL;DR: The protective effect of HAART was greatest in symptomatic patients and those with advanced immune suppression, and the incidence of HIV-1-associated tuberculosis was reduced in an area endemic with tuberculosis and HIV- 1.
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Diagnostic point-of-care tests in resource-limited settings
Paul K. Drain,Emily P. Hyle,Farzad Noubary,Farzad Noubary,Farzad Noubary,Kenneth A. Freedberg,Douglas Wilson,William R. Bishai,William Rodriguez,Ingrid V. Bassett +9 more
TL;DR: A framework for the assessment of point-of-care tests is proposed, and the term test efficacy is suggested to describe the ability of a diagnostic test to support a clinical decision within its operational context, and revised criteria for an ideal diagnostic point- of-care test in resource-limited settings are proposed.
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Determinants of Mortality in a Combined Cohort of 501 Patients With HIV-Associated Cryptococcal Meningitis: Implications for Improving Outcomes
Joseph N Jarvis,Tihana Bicanic,Angela Loyse,Daniel Namarika,Arthur Jackson,Jesse C. Nussbaum,Jesse C. Nussbaum,Nicky Longley,Nicky Longley,Conrad Muzoora,Jacob Phulusa,Kabanda Taseera,Creto Kanyembe,Douglas Wilson,Mina C. Hosseinipour,Annemarie E. Brouwer,Direk Limmathurotsakul,Nicholas J. White,Nicholas J. White,Charles van der Horst,Robin Wood,Graeme Meintjes,Graeme Meintjes,John S. Bradley,Shabbar Jaffar,Thomas S. Harrison +25 more
TL;DR: Cerebrospinal fluid fungal burden, altered mental status, and rate of clearance of infection predict acute mortality in HIV-associated cryptococcal meningitis.
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Comparison of the Early Fungicidal Activity of High-Dose Fluconazole, Voriconazole, and Flucytosine as Second-Line Drugs Given in Combination With Amphotericin B for the Treatment of HIV-Associated Cryptococcal Meningitis
Angela Loyse,Douglas Wilson,Graeme Meintjes,Joseph N Jarvis,Tihana Bicanic,Leesa Bishop,Kevin Rebe,Anthony Williams,Shabbar Jaffar,Linda-Gail Bekker,Robin Wood,Thomas S. Harrison +11 more
TL;DR: AmB plus fluconazole (800-1200 mg/day) represents an immediately implementable alternative to AmB plus 5-FC and is an effective alternative combination in patients not receiving interacting medications for the treatment of HIV-associated cryptococcal meningitis.
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Patient and provider delay in tuberculosis suspects from communities with a high HIV prevalence in South Africa: A cross-sectional study
TL;DR: Delay in TB diagnosis was more attributable to provider than patient delay, and provider delay was associated with increased mortality.