E. Le Chatelier

TL;DR: In this article , the authors performed shotgun-metagenomics-based microbiome profiling in a large cohort of patients with advanced NSCLC (n = 338) treated with first- or second-line ICIs to prospectively validate the predictive value of fecal Akk.

TL;DR: In this paper , the authors used a study design that recapitulates disease initiation, escalation and response to treatment over time, mirroring a longitudinal study that would otherwise be difficult to perform given the protracted nature of IHD pathogenesis.

TL;DR: Oral supplementation with the polyphenol-rich berry camu-camu in mice shifted gut microbial composition, which translated into antitumor activity and a stronger anti-PD-1 response, and castalagin, an ellagitannin, was identified as the active compound in CC.

TL;DR: Strategies combining biotin and prebiotic supplementation could help prevent the deterioration of metabolic states in severe obesity.

TL;DR: Increasing the diversity of DF in a daily consumed product modifies gut microbiota composition and function and could be a relevant nutritional tool to improve cardiometabolic profile.