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Corentin Richard

Researcher at Université de Montréal

Publications -  70
Citations -  5035

Corentin Richard is an academic researcher from Université de Montréal. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 13, co-authored 47 publications receiving 2779 citations. Previous affiliations of Corentin Richard include University of Burgundy.

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Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy, +76 more
- 05 Jan 2018 - 
TL;DR: It is found that primary resistance to ICIs can be attributed to abnormal gut microbiome composition, and Antibiotics inhibited the clinical benefit of ICIs in patients with advanced cancer.
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Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.

Aurélie Fluckiger, +64 more
- 21 Aug 2020 - 
TL;DR: In renal and lung cancer patients, the presence of the enterococcal prophage in stools and expression of a TMP–cross-reactive antigen by tumors correlated with long-term benefit of PD-1 blockade therapy.
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Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors.

TL;DR: Patients who received ATB 30 days prior to the administration of ICI experienced more primary resistance (progressive disease), and progression-free survival was significantly shorter, suggesting that ATB use within 30 days before ICI initiation in patients with advanced melanoma may adversely affect patient outcomes.