F
Fabio Cumbo
Researcher at University of Trento
Publications - 38
Citations - 1050
Fabio Cumbo is an academic researcher from University of Trento. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 10, co-authored 30 publications receiving 344 citations. Previous affiliations of Fabio Cumbo include Roma Tre University & National Research Council.
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Journal ArticleDOI
Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0.
Francesco Asnicar,Andrew Maltez Thomas,Francesco Beghini,Claudia Mengoni,Serena Manara,Paolo Manghi,Qiyun Zhu,Mattia Bolzan,Fabio Cumbo,Uyen May,Jon G. Sanders,Jon G. Sanders,Moreno Zolfo,Evguenia Kopylova,Edoardo Pasolli,Edoardo Pasolli,Rob Knight,Siavash Mirarab,Curtis Huttenhower,Nicola Segata +19 more
TL;DR: PhyloPhlAn 3.0 can assign genomes from isolate sequencing or MAGs to species-level genome bins built from >230,000 publically available sequences, and reconstructs strain-level phylogenies from among the closest species using clade-specific maximally informative markers.
Journal ArticleDOI
Large-scale genome-wide analysis links lactic acid bacteria from food with the gut microbiome.
Edoardo Pasolli,Francesca De Filippis,Italia E. Mauriello,Fabio Cumbo,Aaron M. Walsh,John Leech,Paul D. Cotter,Nicola Segata,Danilo Ercolini +8 more
TL;DR: A large-scale genome-wide comparative analysis of publicly available and newly sequenced food and human metagenomes is performed to investigate the prevalence and diversity of lactic acid bacteria (LAB), indicating food as a major source of LAB species in the human gut.
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Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer
Lisa Derosa,Bertrand Routy,Andrew Maltez Thomas,Valerio Iebba,Gérard Zalcman,Sylvie Friard,Julien Mazieres,Clarisse Audigier-Valette,Denis Moro-Sibilot,François Goldwasser,Carolina Alves Costa Silva,Safae Terrisse,Mélodie Bonvalet,Arnaud Scherpereel,H. Pegliasco,Corentin Richard,François Ghiringhelli,Arielle Elkrief,Antoine Désilets,F. Blanc-Durand,Fabio Cumbo,Aitor Abuin Blanco,Romain Boidot,Sandy Chevrier,Romain Daillère,Guido Kroemer,Laurie Alla,Nicolas Pons,E. Le Chatelier,Nathalie Galleron,Hugo Roume,Agathe Dubuisson,M. Bouchard,Meriem Messaoudene,Damien Drubay,Eric Deutsch,Fabrice Barlesi,David Planchard,Nicola Segata,Stéphanie Martinez,Laurence Zitvogel,Jean-Charles Soria,Benjamin Besse +42 more
TL;DR: In this article , the authors performed shotgun-metagenomics-based microbiome profiling in a large cohort of patients with advanced NSCLC (n = 338) treated with first- or second-line ICIs to prospectively validate the predictive value of fecal Akk.
Journal ArticleDOI
A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity.
David Wylensek,Thomas C. A. Hitch,Thomas Riedel,Afrizal Afrizal,Neeraj Kumar,Neeraj Kumar,Esther Wortmann,Tianzhe Liu,Saravanan Devendran,Till Robin Lesker,Sara B. Hernández,Viktoria Heine,Eva Miriam Buhl,Paul M. D'Agostino,Fabio Cumbo,Thomas Fischöder,Marzena Wyschkon,Torey Looft,Valeria R. Parreira,Birte Abt,Heidi L. Doden,Lindsey Ly,João M. P. Alves,Markus Reichlin,Krzysztof Flisikowski,Laura Navarro Suarez,Anthony P. Neumann,Garret Suen,Tomas de Wouters,Sascha Rohn,Sascha Rohn,Ilias Lagkouvardos,Emma Allen-Vercoe,Cathrin Spröer,Boyke Bunk,Anja J. Taverne-Thiele,Marcel Giesbers,Jerry M. Wells,Klaus Neuhaus,Angelika Schnieke,Felipe Cava,Nicola Segata,Lothar Elling,Till Strowig,Jason M. Ridlon,Tobias A. M. Gulder,Jörg Overmann,Thomas Clavel +47 more
TL;DR: Meta-analysis of 16S rRNA amplicon sequence data and metagenome-assembled genomes reveal prevalent and pig-specific species within Lactobacillus, Streptococcus, Clostridium, Desulfovibrio, Enterococcus and Fusobacterium, and several new genera described in this study.
Journal ArticleDOI
Microbial genomes from non-human primate gut metagenomes expand the primate-associated bacterial tree of life with over 1000 novel species
Serena Manara,Francesco Asnicar,Francesco Beghini,Davide Bazzani,Fabio Cumbo,Moreno Zolfo,Eleonora Nigro,Nicolai Karcher,Paolo Manghi,Marisa Isabell Metzger,Edoardo Pasolli,Nicola Segata +11 more
TL;DR: The newly reconstructed species greatly expand the microbial diversity associated with NHPs, thus enabling better interrogation of the primate microbiome and empowering in-depth human and non-human comparative and co-diversification studies.