A
Andrew Maltez Thomas
Researcher at University of Trento
Publications - 45
Citations - 3991
Andrew Maltez Thomas is an academic researcher from University of Trento. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 17, co-authored 33 publications receiving 1361 citations. Previous affiliations of Andrew Maltez Thomas include University of São Paulo.
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Journal ArticleDOI
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
Jakob Wirbel,Paul Theodor Pyl,Paul Theodor Pyl,Ece Kartal,Konrad Zych,Alireza Kashani,Alessio Milanese,Jonas S. Fleck,Anita Y. Voigt,Albert Pallejà,Ruby Ponnudurai,Shinichi Sunagawa,Luis Pedro Coelho,Petra Schrotz-King,Emily Vogtmann,Nina Habermann,Emma Niméus,Andrew Maltez Thomas,Andrew Maltez Thomas,Paolo Manghi,Sara Gandini,Davide Serrano,Sayaka Mizutani,Sayaka Mizutani,Hirotsugu Shiroma,Satoshi Shiba,Tatsuhiro Shibata,Shinichi Yachida,Takuji Yamada,Takuji Yamada,Levi Waldron,Alessio Naccarati,Nicola Segata,Rashmi Sinha,Cornelia M. Ulrich,Hermann Brenner,Manimozhiyan Arumugam,Manimozhiyan Arumugam,Peer Bork,Georg Zeller +39 more
TL;DR: A meta-analysis of eight geographically and technically diverse fecal shotgun metagenomic studies of colorectal cancer identified a core set of 29 species significantly enriched in CRC metagenomes, establishing globally generalizable, predictive taxonomic and functional microbiome CRC signatures as a basis for future diagnostics.
Journal ArticleDOI
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with biobakery 3
Francesco Beghini,Lauren J. McIver,Aitor Blanco-Míguez,Leonard Dubois,Francesco Asnicar,Sagun Maharjan,Sagun Maharjan,Ana Mailyan,Ana Mailyan,Paolo Manghi,Matthias Scholz,Andrew Maltez Thomas,Mireia Valles-Colomer,George Weingart,George Weingart,Yancong Zhang,Yancong Zhang,Moreno Zolfo,Curtis Huttenhower,Curtis Huttenhower,Eric A. Franzosa,Eric A. Franzosa,Nicola Segata,Nicola Segata +23 more
TL;DR: BioBakery 3 as mentioned in this paper is a set of integrated, improved methods for taxonomic, strain-level, functional, and phylogenetic profiling of metagenomes newly developed to build on the largest set of reference sequences now available.
Journal ArticleDOI
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
Andrew Maltez Thomas,Andrew Maltez Thomas,Paolo Manghi,Francesco Asnicar,Edoardo Pasolli,Federica Armanini,Moreno Zolfo,Francesco Beghini,Serena Manara,Nicolai Karcher,Chiara Pozzi,Sara Gandini,Davide Serrano,Sonia Tarallo,Antonio Francavilla,Gaetano Gallo,Mario Trompetto,Giulio Ferrero,Sayaka Mizutani,Sayaka Mizutani,Hirotsugu Shiroma,Satoshi Shiba,Tatsuhiro Shibata,Shinichi Yachida,Takuji Yamada,Takuji Yamada,Jakob Wirbel,Petra Schrotz-King,Cornelia M. Ulrich,Hermann Brenner,Manimozhiyan Arumugam,Manimozhiyan Arumugam,Peer Bork,Georg Zeller,Francesca Cordero,Emmanuel Dias-Neto,João C. Setubal,João C. Setubal,Adrian Tett,Barbara Pardini,Maria Rescigno,Levi Waldron,Alessio Naccarati,Nicola Segata +43 more
TL;DR: The combined analysis of heterogeneous CRC cohorts identified reproducible microbiome biomarkers and accurate disease-predictive models that can form the basis for clinical prognostic tests and hypothesis-driven mechanistic studies.
Posted ContentDOI
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3
Francesco Beghini,Lauren J. McIver,Aitor Blanco-Míguez,Leonard Dubois,Francesco Asnicar,Sagun Maharjan,Sagun Maharjan,Ana Mailyan,Ana Mailyan,Andrew Maltez Thomas,Paolo Manghi,Mireia Valles-Colomer,George Weingart,George Weingart,Yancong Zhang,Yancong Zhang,Moreno Zolfo,Curtis Huttenhower,Curtis Huttenhower,Eric A. Franzosa,Eric A. Franzosa,Nicola Segata,Nicola Segata +22 more
TL;DR: With open-source implementations and cloud-deployable reproducible workflows, the bioBakery 3 platform can help researchers deepen the resolution, scale, and accuracy of multi-omic profiling for microbial community studies.
Journal ArticleDOI
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals.
Francesco Asnicar,Sarah Berry,Ana M. Valdes,Ana M. Valdes,Long H. Nguyen,Gianmarco Piccinno,David A. Drew,Emily R Leeming,Rachel J. Gibson,Caroline I. Le Roy,Haya Al Khatib,Lucy Francis,Mohsen Mazidi,Olatz Mompeo,Mireia Valles-Colomer,Adrian Tett,Francesco Beghini,Leonard Dubois,Davide Bazzani,Andrew Maltez Thomas,Chloe Mirzayi,Asya Khleborodova,Sehyun Oh,Rachel Hine,Christopher Bonnett,Joan Capdevila,Serge Danzanvilliers,Francesca Giordano,Ludwig Geistlinger,Levi Waldron,Richard Davies,George Hadjigeorgiou,Jonathan Wolf,Jose M. Ordovas,Jose M. Ordovas,Christopher D. Gardner,Paul W. Franks,Paul W. Franks,Andrew T. Chan,Andrew T. Chan,Curtis Huttenhower,Curtis Huttenhower,Tim D. Spector,Nicola Segata,Nicola Segata +44 more
TL;DR: This paper performed deep metagenomic sequencing of 1,203 gut microbiomes from 1,098 individuals enrolled in the Personalised Responses to Dietary Composition Trial (PREDICT 1) study, whose detailed longterm diet information, as well as hundreds of fasting and same-meal post-prandial cardiometabolic blood marker measurements were available.