E
Edmund Godfrey
Researcher at Cambridge University Hospitals NHS Foundation Trust
Publications - 25
Citations - 843
Edmund Godfrey is an academic researcher from Cambridge University Hospitals NHS Foundation Trust. The author has contributed to research in topics: Transplantation & Pancreatic cancer. The author has an hindex of 7, co-authored 25 publications receiving 468 citations.
Papers
More filters
Journal ArticleDOI
Guidelines on the management of abnormal liver blood tests
Philip N. Newsome,R Cramb,Suzanne Davison,John F. Dillon,Mark Foulerton,Edmund Godfrey,Richard Hall,Ulrike Harrower,Mark Hudson,Andrew Langford,Anne Mackie,Robert Mitchell-Thain,Karen Sennett,Nick Sheron,Julia Verne,Martine Walmsley,Andrew Yeoman +16 more
TL;DR: These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG.
Journal ArticleDOI
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
Fotios Sampaziotis,Alexander W. Justin,Olivia C. Tysoe,Stephen J. Sawiak,Edmund Godfrey,Sara Upponi,Richard L. Gieseck,Miguel Cardoso de Brito,N.L. Berntsen,María J Gómez-Vázquez,Daniel Ortmann,Loukia Yiangou,Alexander Ross,Johannes Bargehr,Alessandro Bertero,Mariëlle C. F. Zonneveld,Marianne Terndrup Pedersen,Matthias Pawlowski,Laura Valestrand,Pedro Madrigal,Nikitas Georgakopoulos,Negar Pirmadjid,Gregor Skeldon,John Casey,Wenmiao Shu,Wenmiao Shu,Paulina M. Materek,Kirsten E. Snijders,Stephanie Brown,Casey A. Rimland,Ingrid Simonic,Susan E. Davies,Kim B. Jensen,Matthias Zilbauer,William Gelson,Graeme J.M. Alexander,Sanjay Sinha,Nicholas R.F. Hannan,Thomas A. Wynn,Tom H. Karlsen,Espen Melum,Athina E. Markaki,Kourosh Saeb-Parsy,Ludovic Vallier +43 more
TL;DR: In conclusion, ECOs can successfully reconstruct the biliary tree, providing proof of principle for organ regeneration using human primary cholangiocytes expanded in vitro.
Journal ArticleDOI
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Fotios Sampaziotis,Fotios Sampaziotis,Daniele Muraro,Olivia C. Tysoe,Stephen J. Sawiak,Timothy E. Beach,Edmund Godfrey,Sara Upponi,Teresa Brevini,Brandon T Wesley,Jose Garcia-Bernardo,Krishnaa T. Mahbubani,Giovanni Canu,Richard L. Gieseck,N.L. Berntsen,N.L. Berntsen,Victoria L. Mulcahy,Keziah Crick,Corrina Fear,Sharayne Robinson,Lisa Swift,Laure Gambardella,Johannes Bargehr,Daniel Ortmann,Stephanie Brown,Anna Osnato,Michael P. Murphy,Gareth Corbett,William Gelson,William Gelson,George F. Mells,George F. Mells,Peter C. Humphreys,Susan E. Davies,Irum Amin,Irum Amin,Paul Gibbs,Paul Gibbs,Sanjay Sinha,Sarah A. Teichmann,Sarah A. Teichmann,Andrew J. Butler,Andrew J. Butler,Teik Choon See,Espen Melum,Christopher J.E. Watson,Kourosh Saeb-Parsy,Kourosh Saeb-Parsy,Ludovic Vallier +48 more
TL;DR: In this paper, the authors used single-cell RNA sequencing to show that primary human cholangiocytes display transcriptional diversity that is lost in organoid culture, and used this property to repair human intrahepatic ducts after transplantation.
Journal ArticleDOI
CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response
Daniele Biasci,Martin Smoragiewicz,Claire M. Connell,Claire M. Connell,Zhikai Wang,Ya Gao,James Thaventhiran,Bristi Basu,Bristi Basu,Lukasz Magiera,T. Isaac Johnson,Lisa Bax,Aarthi Gopinathan,Christopher Isherwood,Ferdia A. Gallagher,Maria Pawula,Irena Hudecova,Davina Gale,Nitzan Rosenfeld,Petros Barmpounakis,Elizabeta C. Popa,Rebecca Brais,Edmund Godfrey,Fraz Mir,Frances M. Richards,Douglas T. Fearon,Douglas T. Fearon,Douglas T. Fearon,Tobias Janowitz,Duncan I. Jodrell +29 more
TL;DR: In this article, the authors showed that CXCL12-stimulated CXCR4 inhibits the directed migration mediated by all of the immune cell types that participate in an integrated immune response.
Journal ArticleDOI
Pancreatic allograft thrombosis: Suggestion for a CT grading system and management algorithm
Abdul R. Hakeem,John Chen,S. Iype,Menna R. Clatworthy,Christopher J.E. Watson,Edmund Godfrey,Sara Upponi,Kourosh Saeb-Parsy +7 more
TL;DR: The data suggest that therapeutic anticoagulation is not necessary for grade 1 and 2 arterial and grade 1 venous thrombosis, and the proposed grading system can assist clinicians in decision‐making and provide standardized reporting for future studies.