E
Edward A. Liechty
Researcher at Indiana University
Publications - 137
Citations - 5143
Edward A. Liechty is an academic researcher from Indiana University. The author has contributed to research in topics: Population & Pregnancy. The author has an hindex of 40, co-authored 128 publications receiving 4258 citations. Previous affiliations of Edward A. Liechty include Indiana University – Purdue University Indianapolis & Harvard University.
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Journal ArticleDOI
A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial
Fernando Althabe,José M. Belizán,Elizabeth M. McClure,Jennifer Hemingway-Foday,Mabel Berrueta,Agustina Mazzoni,Alvaro Ciganda,Shivaprasad S. Goudar,Bhalachandra S. Kodkany,Niranjana S. Mahantshetti,Sangappa M. Dhaded,Geetanjali Katageri,Mrityunjay C Metgud,Anjali M Joshi,Mrutyunjaya B Bellad,Narayan V Honnungar,Richard J. Derman,Sarah Saleem,Omrana Pasha,Sumera Aziz Ali,Farid Hasnain,Robert L. Goldenberg,Fabian Esamai,Paul Nyongesa,Silas Ayunga,Edward A. Liechty,Ana Garces,Lester Figueroa,K. Michael Hambidge,Nancy F. Krebs,Archana Patel,Anjali Bhandarkar,Manjushri Waikar,Patricia L. Hibberd,Elwyn Chomba,Waldemar A. Carlo,Angel Mwiche,Melody Chiwila,Albert Manasyan,Sayury Pineda,Sreelatha Meleth,Vanessa Thorsten,Kristen Stolka,Dennis Wallace,Marion Koso-Thomas,Alan H. Jobe,Pierre Buekens +46 more
TL;DR: Despite increased use of antenatal corticosteroids in low-birthweight infants in the intervention groups, neonatal mortality did not decrease in this group, and increased in the population overall, and the risk of maternal infection seems to have been increased.
Journal ArticleDOI
Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway
Wuqiang Zhu,Mark H. Soonpaa,Hanying Chen,Weihua Shen,R. Mark Payne,Edward A. Liechty,Randall L. Caldwell,Weinian Shou,Loren J. Field +8 more
TL;DR: It is suggested that doxorubicin treatment induces acute cardiac dysfunction and reduces cardiac mass via p53-dependent inhibition of mTOR signaling and that loss of myocardial mass, and not cardiomyocyte apoptosis, is the major contributor to acute doxorbicin cardiotoxicity.
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Adverse maternal and perinatal outcomes in adolescent pregnancies: The Global Network’s Maternal Newborn Health Registry study
Fernando Althabe,Janet Moore,Luz Gibbons,Mabel Berrueta,Shivaprasad S. Goudar,Elwyn Chomba,Richard J. Derman,Archana Patel,Sarah Saleem,Omrana Pasha,Fabian Esamai,Ana Garces,Edward A. Liechty,K. Michael Hambidge,Nancy F. Krebs,Patricia L. Hibberd,Robert L. Goldenberg,Marion Koso-Thomas,Waldemar A. Carlo,Maria Luisa Cafferata,Pierre Buekens,Elizabeth M. McClure +21 more
TL;DR: This study suggests that pregnancy among adolescents is not associated with better maternal outcomes, but is associated with worse perinatal outcomes, particularly in younger adolescents, however, this may not be the case in regions like South Asia where there are decreasing rates of adolescent pregnancies.
Journal ArticleDOI
Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial
Matthew K. Hoffman,Shivaprasad S. Goudar,Bhalachandra S. Kodkany,Mrityunjay C Metgud,Manjunath S Somannavar,Jean Okitawutshu,Adrien Lokangaka,Antoinette Tshefu,Carl L. Bose,Abigail Mwapule,Musaku Mwenechanya,Elwyn Chomba,Waldemar A. Carlo,Javier Chicuy,Lester Figueroa,Ana Garces,Nancy F. Krebs,Saleem Jessani,Farnaz Zehra,Sarah Saleem,Robert L. Goldenberg,Kunal Kurhe,Prabir Kumar Das,Archana Patel,Patricia L. Hibberd,Emmah Achieng,Paul Nyongesa,Fabian Esamai,Edward A. Liechty,Norman Goco,Jennifer Hemingway-Foday,Janet Moore,Tracy L. Nolen,Elizabeth M. McClure,Marion Koso-Thomas,Menachem Miodovnik,Robert M. Silver,Richard J. Derman +37 more
TL;DR: In populations of nulliparous women with singleton pregnancies from low-income and middle-income countries, low-dose aspirin initiated between 6 weeks and 0 days of gestation and 13 weeks and 6 days of pregnancy resulted in a reduced incidence of preterm delivery before 37 weeks, and reduced perinatal mortality.
Journal ArticleDOI
Risk factors for maternal death and trends in maternal mortality in low- and middle-income countries: a prospective longitudinal cohort analysis
Melissa Bauserman,Adrien Lokangaka,Vanessa Thorsten,Antoinette Tshefu,Shivaprasad S. Goudar,Fabian Esamai,Ana Garces,Sarah Saleem,Omrana Pasha,Archana Patel,Albert Manasyan,Mabel Berrueta,Bhala Kodkany,Elwyn Chomba,Edward A. Liechty,K. Michael Hambidge,Nancy F. Krebs,Richard J. Derman,Patricia L. Hibberd,Fernando Althabe,Waldemar A. Carlo,Marion Koso-Thomas,Robert L. Goldenberg,Dennis Wallace,Elizabeth M. McClure,Carl L. Bose +25 more
TL;DR: The MNHR identified preventable causes of maternal mortality in diverse settings in low- and middle-income countries and can be used to monitor public health strategies and determine their association with reducing maternal mortality.