E
Edward F. DiCarlo
Researcher at Hospital for Special Surgery
Publications - 107
Citations - 8087
Edward F. DiCarlo is an academic researcher from Hospital for Special Surgery. The author has contributed to research in topics: Arthritis & Rheumatoid arthritis. The author has an hindex of 45, co-authored 99 publications receiving 7079 citations. Previous affiliations of Edward F. DiCarlo include Cornell University & University of Massachusetts Medical School.
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Journal ArticleDOI
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Fan Zhang,Kevin Wei,Kamil Slowikowski,Chamith Y. Fonseka,Deepak A. Rao,Stephen Kelly,Susan M. Goodman,Susan M. Goodman,Darren Tabechian,Laura B. Hughes,Karen Salomon-Escoto,Gerald F. Watts,A. Helena Jonsson,Javier Rangel-Moreno,Nida Meednu,Cristina Rozo,William Apruzzese,Thomas Eisenhaure,David J. Lieb,David L. Boyle,Arthur M. Mandelin,Brendan F. Boyce,Edward F. DiCarlo,Ellen M. Gravallese,Peter K. Gregersen,Larry W. Moreland,Gary S. Firestein,Nir Hacohen,Chad Nusbaum,James A. Lederer,Harris Perlman,Costantino Pitzalis,Andrew Filer,V. Michael Holers,Vivian P. Bykerk,Vivian P. Bykerk,Laura T. Donlin,Laura T. Donlin,Jennifer H. Anolik,Michael B. Brenner,Soumya Raychaudhuri +40 more
TL;DR: Several single-cell -omics approaches are used to define the cellular processes and pathways in the human RA joint and attributed IL6 expression to THY1+HLA-DRAhi fibroblasts and IL1B production to pro-inflammatory monocytes, potentially key mediators of RA pathogenesis.
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The anatomy and histology of the inferior glenohumeral ligament complex of the shoulder
Stephen J. O'Brien,M C Neves,Steven P. Arnoczky,S R Rozbruck,Edward F. DiCarlo,Russell F. Warren,R Schwartz,Thomas L. Wickiewicz +7 more
TL;DR: The gross and histologic anatomy of the inferior glenohumeral ligament was studied in 11 fresh frozen cadaver shoulders and revealed a single structure as an important anterior and posterior stabilizer of the shoulder joint.
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Anatomy, histology, and vascularity of the glenoid labrum. An anatomical study.
Daniel E. Cooper,Steven P. Arnoczky,Stephen J. O'Brien,Russell F. Warren,Edward F. DiCarlo,Answorth A. Allen +5 more
TL;DR: This article studied the gross, histological, and vascular anatomy of the glenoid labrum in twenty-three fresh-frozen shoulders from cadavera to demonstrate its cross-sectional anatomy, its microvascularity, and its attachments.
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FTIR Microspectroscopic Analysis of Human Osteonal Bone
Eleftherios P. Paschalis,Edward F. DiCarlo,F. Betts,Pamela J. Sherman,Richard Mendelsohn,Adele L. Boskey +5 more
TL;DR: Fourier Transform Infrared Microspectroscopy (FTIRM) has been used to study the changes in mineral and matrix content and composition in replicate biopsies of non-osteoporotic human osteonal bone, suggesting their applicability for the analysis of mineral changes in disease.
Journal ArticleDOI
Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis.
Andrew D. Pearle,Carla R. Scanzello,SS George,Lisa A. Mandl,Edward F. DiCarlo,Margaret G. E. Peterson,Thomas P. Sculco,Mary K. Crow +7 more
TL;DR: The results suggest that systemic hsCRP levels reflect synovial inflammation in OA patients, perhaps by means ofsynovial IL-6 production, which is associated with disease progression in patients with osteoarthritis.