E
Elias S.J. Arnér
Researcher at Karolinska Institutet
Publications - 208
Citations - 18978
Elias S.J. Arnér is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Thioredoxin reductase & Thioredoxin. The author has an hindex of 58, co-authored 192 publications receiving 16579 citations. Previous affiliations of Elias S.J. Arnér include City University of New York.
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Posted ContentDOI
System-wide Identification of Enzyme Substrates by Thermal Analysis (SIESTA)
Amir Ata Saei,Juan Astorga Wells,Pierre Sabatier,Christian M. Beusch,Alexey Chernobrovkin,Sergey Rodin,Sergey Rodin,Katja Näreoja,Ann-Gerd Thorsell,Tobias Karlberg,Qing Cheng,Ákos Végvári,Elias S.J. Arnér,Herwig Schüler,Roman A. Zubarev,Roman A. Zubarev +15 more
TL;DR: In this paper, a thermal analysis method called System-Wide Identification of Enzyme Substrates by Thermal Analysis (SIESTA) was proposed to identify enzyme-substrate reactions on a cellular level.
Book ChapterDOI
History of Selenium Research
TL;DR: Selenium research must be said to have began in 1817, when Berzelius discovered this element as mentioned in this paper, and the first genuine publication describing this research was published by Bergzelius in 1818, in a paper where he also named the element as Selenium.
Journal ArticleDOI
Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides
Marián Schwarz,Alina Löser,Qing Chen,Mareike Wichmann-Costaganna,Patrick Schädel,Oliver Werz,Elias S.J. Arnér,Anna P. Kipp +7 more
TL;DR: In this paper , the authors used recombinant human selenoprotein glutathione peroxidases (GPXs) in pure enzyme assays to study their substrate specificities side by side.
Journal ArticleDOI
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
F. Fata,Radosveta Gencheva,Qing Chen,R De Lullo,Matteo Ardini,Ida Silvestri,Federica Gabriele,Rodolfo Ippoliti,Christina A. Bulman,Judy A. Sakanari,David R. Williams,Elias S.J. Arnér,Francesco Angelucci +12 more
TL;DR: In this article , the authors characterized the thioredoxin reductase (TrxR) selenoproteins from Brugia malayi and Onchocerca volvulus, filarial nematode parasites and causative agents of lymphatic filariasis and onchocerciasis.
Posted ContentDOI
System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
Amir Ata Saei,Christian M. Beusch,Pierre Sabatier,Juan Astorga Wells,Alexey Chernobrovkin,Sergey Rodin,Sergey Rodin,Katja Näreoja,Ann-Gerd Thorsell,Tobias Karlberg,Qing Cheng,Susanna L. Lundström,Massimiliano Gaetani,Ákos Végvári,Elias S.J. Arnér,Herwig Schüler,Roman A. Zubarev,Roman A. Zubarev +17 more
TL;DR: System-wide Identification of Enzyme Substrates by Thermal Analysis (SIESTA) assumes that enzymatic post-translational modification of substrate proteins changes their thermal stability, and applies the concept of specificity to reveal potential substrates.