E
Elina Ikonen
Researcher at Minerva Foundation Institute for Medical Research
Publications - 207
Citations - 26902
Elina Ikonen is an academic researcher from Minerva Foundation Institute for Medical Research. The author has contributed to research in topics: Endosome & Lipid droplet. The author has an hindex of 60, co-authored 197 publications receiving 24542 citations. Previous affiliations of Elina Ikonen include University of Helsinki & University of Geneva.
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Journal Article
Semliki Forest virus as a tool for protein expression in cultured rat hippocampal neurons.
TL;DR: The SFV expression system is suitable for short-term expression of proteins and can be used successfully to study the polarized distribution of heterologous proteins expressed in cultured hippocampal neurons.
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Expression of aspartylglucosaminidase in human tissues from normal individuals and aspartylglucosaminuria patients.
TL;DR: Both heavy methylation of the AGA gene and the constant level of AGA mRNA were typical of a "house-hold" type of enzyme that can be found in small quantities in all tissues, suggesting that the expression of AGA is regulated not at the transcriptional but rather at the translational level.
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Huntington disease in Finland: a molecular and genealogical study
TL;DR: A continuation to the restriction fragment length polymorphism haplotype analysis, in combination with a genealogical study of all the Finnish HD families, concludes that the HD gene(s) has most probably arrived in Finland on several occasions via foreign immigrants during the last few centuries.
Journal Article
Finnish disease heritage
TL;DR: The Finnish disease heritage refers to rare hereditary diseases that occur in the Finnish population in a relatively larger proportion than in other populations, and the genes underlying all of the 36 diseases have been identified.
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HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo
Burcin Gungor,Lauri Vanharanta,Maarit Hölttä-Vuori,Juho Pirhonen,Nikolaj H.T. Petersen,Silvia Gramolelli,Päivi M. Ojala,Thomas Kirkegaard,Elina Ikonen,Elina Ikonen +9 more
TL;DR: It is demonstrated that HSP70 exerts a cholesterol lowering effect in primary human cells and animals and a nuclear action of H SP70 in mediating cross-talk between HSP and LXR transcriptional regulation is uncovered.