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Els Beghein

Researcher at Ghent University

Publications -  4
Citations -  995

Els Beghein is an academic researcher from Ghent University. The author has contributed to research in topics: Extracellular vesicle & Actin-binding protein. The author has an hindex of 4, co-authored 4 publications receiving 701 citations.

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Journal ArticleDOI

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van Deun, +101 more
- 01 Mar 2017 - 
TL;DR: It is argued that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments and EV-TRACK, a crowdsourcing knowledgebase that centralizes EV biology and methodology, is described.
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Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein-Protein Interaction Analysis, and Protein Function Exploration.

TL;DR: The use of nanobodies as detection reagents in fluorescence microscopy and focus on recent advances in super-resolution microscopy are discussed and the potential value of nanOBodies in studying protein function is discussed, and their recently reported application in targeted protein degradation is discussed.
Journal ArticleDOI

Cortactin and fascin-1 regulate extracellular vesicle release by controlling endosomal trafficking or invadopodia formation and function

TL;DR: It is reported that both cortactin and fascin-1 play key roles in EV release by regulating endosomal trafficking or invadopodia formation and function.
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A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles

TL;DR: An alpaca survivin nanobody (SVVNb8) that binds with low nanomolar affinity to its target and can serve as a model system to investigate mitochondrial and peroxisomal (survivin) protein import.