G
Glenn Vergauwen
Researcher at Ghent University Hospital
Publications - 16
Citations - 1308
Glenn Vergauwen is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Extracellular vesicle & Medicine. The author has an hindex of 6, co-authored 11 publications receiving 840 citations. Previous affiliations of Glenn Vergauwen include Ghent University.
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Journal ArticleDOI
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun,Pieter Mestdagh,Patrizia Agostinis,Özden Akay,Sushma Anand,Jasper Anckaert,Zoraida Andreu Martinez,Tine Baetens,Els Beghein,Laurence Bertier,Geert Berx,Janneke Boere,Stephanie Boukouris,Michel Bremer,Dominik Buschmann,James Brian Byrd,Clara Casert,Lesley Cheng,Anna Cmoch,Delphine Daveloose,Eva De Smedt,Seyma Demirsoy,Victoria Depoorter,Bert Dhondt,Tom A. P. Driedonks,Aleksandra M. Dudek,Abdou ElSharawy,Ilaria Floris,Andrew D Foers,Kathrin Gärtner,Abhishek D. Garg,Edward Geeurickx,Jan Gettemans,Farzaneh Ghazavi,Bernd Giebel,Tom Groot Kormelink,Grace V. Hancock,Hetty Helsmoortel,Andrew F. Hill,Vincent Hyenne,Hina Kalra,David Kim,Joanna Kowal,Joanna Kowal,Sandra Kraemer,Petra Leidinger,Carina Leonelli,Yaxuan Liang,Lien Lippens,Shu Liu,Alessandra Lo Cicero,Alessandra Lo Cicero,Shaun Martin,Suresh Mathivanan,Prabhu Mathiyalagan,Tamás Matusek,Gloria Milani,Marta Monguió-Tortajada,Liselot Mus,Dillon C. Muth,Andrea Németh,Esther N. M. Nolte-‘t Hoen,Lorraine O'Driscoll,Roberta Palmulli,Roberta Palmulli,Michael W. Pfaffl,Bjarke Primdal-Bengtson,Bjarke Primdal-Bengtson,Erminia Romano,Quentin Rousseau,Susmita Sahoo,Natalia G. Sampaio,Monisha Samuel,Benjamin J. Scicluna,Bieke Soen,Anneleen Steels,Johannes V. Swinnen,Maarit Takatalo,Safia Thaminy,Clotilde Théry,Clotilde Théry,Joeri Tulkens,Isabel Van Audenhove,Susanne G. van der Grein,Alan Van Goethem,Martijn J. C. van Herwijnen,Guillaume van Niel,Guillaume van Niel,Nadine Van Roy,Alexander R. van Vliet,Niels Vandamme,Suzanne Vanhauwaert,Glenn Vergauwen,Frederik J. Verweij,Frederik J. Verweij,Annelynn Wallaert,Marca H. M. Wauben,Kenneth W. Witwer,Marijke I. Zonneveld,Olivier De Wever,Jo Vandesompele,An Hendrix +101 more
TL;DR: It is argued that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments and EV-TRACK, a crowdsourcing knowledgebase that centralizes EV biology and methodology, is described.
Journal ArticleDOI
Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research
Glenn Vergauwen,Glenn Vergauwen,Bert Dhondt,Bert Dhondt,Jan Van Deun,Eva De Smedt,Geert Berx,Evy Timmerman,Kris Gevaert,Ilkka Miinalainen,Veronique Cocquyt,Geert Braems,Rudy Van den Broecke,Hannelore Denys,Olivier De Wever,An Hendrix +15 more
TL;DR: Choice of centrifugal filters and protein assays confound EV analysis and should be carefully considered to increase efficiency towards biomarker discovery.
Journal ArticleDOI
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction.
Joeri Tulkens,Glenn Vergauwen,Jan Van Deun,Edward Geeurickx,Bert Dhondt,Lien Lippens,Marie-Angélique De Scheerder,Ilkka Miinalainen,Pekka Rappu,Bruno G. De Geest,Katrien Vandecasteele,Debby Laukens,Linos Vandekerckhove,Hannelore Denys,Jo Vandesompele,Olivier De Wever,An Hendrix +16 more
TL;DR: Fractionated plasma of 49 subjects is fractionated to distinguish bacterial EV-associated LPS from other LPS products, which may deliver and elicit a variety of immunological and metabolic responses in different organs including the brain.
Journal ArticleDOI
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Bert Dhondt,Edward Geeurickx,Joeri Tulkens,Jan Van Deun,Glenn Vergauwen,Lien Lippens,Ilkka Miinalainen,Pekka Rappu,Jyrki Heino,Piet Ost,Nicolaas Lumen,Olivier De Wever,An Hendrix +12 more
TL;DR: This study identifies hundreds of previously undetected proteins in uEV of prostate cancer patients and provides a powerful toolbox to map uEV content and contaminants ultimately allowing biomarker discovery in urological cancers.
Journal ArticleDOI
The Generation and Use of Recombinant Extracellular Vesicles as Biological Reference Material
Edward Geeurickx,Joeri Tulkens,Bert Dhondt,Bert Dhondt,Jan Van Deun,Lien Lippens,Lien Lippens,Glenn Vergauwen,Glenn Vergauwen,Elisa Heyrman,Delphine De Sutter,Kris Gevaert,Francis Impens,Ilkka Miinalainen,Pieter-Jan Van Bockstal,Thomas De Beer,Marca H. M. Wauben,Esther N. M. Nolte-‘t-Hoen,Katarzyna Bloch,Johannes V. Swinnen,Edwin van der Pol,Rienk Nieuwland,Geert Braems,Nico Callewaert,Pieter Mestdagh,Jo Vandesompele,Hannelore Denys,Sven Eyckerman,Olivier De Wever,An Hendrix +29 more
TL;DR: HIV-derived gag proteins are used to assemble recombinant fluorescent EV as a trackable reference material resembling the physical and biochemical properties of sample EV, which will aid EV-based sample preparation and analysis, data normalization, method development and instrument calibration in various research and biomedical applications.