F
Farzaneh Ghazavi
Researcher at Ghent University Hospital
Publications - 15
Citations - 1066
Farzaneh Ghazavi is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Leukemia & Age of onset. The author has an hindex of 10, co-authored 14 publications receiving 747 citations. Previous affiliations of Farzaneh Ghazavi include University of Tehran & Ghent University.
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EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun,Pieter Mestdagh,Patrizia Agostinis,Özden Akay,Sushma Anand,Jasper Anckaert,Zoraida Andreu Martinez,Tine Baetens,Els Beghein,Laurence Bertier,Geert Berx,Janneke Boere,Stephanie Boukouris,Michel Bremer,Dominik Buschmann,James Brian Byrd,Clara Casert,Lesley Cheng,Anna Cmoch,Delphine Daveloose,Eva De Smedt,Seyma Demirsoy,Victoria Depoorter,Bert Dhondt,Tom A. P. Driedonks,Aleksandra M. Dudek,Abdou ElSharawy,Ilaria Floris,Andrew D Foers,Kathrin Gärtner,Abhishek D. Garg,Edward Geeurickx,Jan Gettemans,Farzaneh Ghazavi,Bernd Giebel,Tom Groot Kormelink,Grace V. Hancock,Hetty Helsmoortel,Andrew F. Hill,Vincent Hyenne,Hina Kalra,David Kim,Joanna Kowal,Joanna Kowal,Sandra Kraemer,Petra Leidinger,Carina Leonelli,Yaxuan Liang,Lien Lippens,Shu Liu,Alessandra Lo Cicero,Alessandra Lo Cicero,Shaun Martin,Suresh Mathivanan,Prabhu Mathiyalagan,Tamás Matusek,Gloria Milani,Marta Monguió-Tortajada,Liselot Mus,Dillon C. Muth,Andrea Németh,Esther N. M. Nolte-‘t Hoen,Lorraine O'Driscoll,Roberta Palmulli,Roberta Palmulli,Michael W. Pfaffl,Bjarke Primdal-Bengtson,Bjarke Primdal-Bengtson,Erminia Romano,Quentin Rousseau,Susmita Sahoo,Natalia G. Sampaio,Monisha Samuel,Benjamin J. Scicluna,Bieke Soen,Anneleen Steels,Johannes V. Swinnen,Maarit Takatalo,Safia Thaminy,Clotilde Théry,Clotilde Théry,Joeri Tulkens,Isabel Van Audenhove,Susanne G. van der Grein,Alan Van Goethem,Martijn J. C. van Herwijnen,Guillaume van Niel,Guillaume van Niel,Nadine Van Roy,Alexander R. van Vliet,Niels Vandamme,Suzanne Vanhauwaert,Glenn Vergauwen,Frederik J. Verweij,Frederik J. Verweij,Annelynn Wallaert,Marca H. M. Wauben,Kenneth W. Witwer,Marijke I. Zonneveld,Olivier De Wever,Jo Vandesompele,An Hendrix +101 more
TL;DR: It is argued that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments and EV-TRACK, a crowdsourcing knowledgebase that centralizes EV biology and methodology, is described.
Journal ArticleDOI
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia
Hetty Helsmoortel,Hetty Helsmoortel,Silvia Bresolin,Tim Lammens,Hélène Cavé,Peter Noellke,Aurélie Caye,Farzaneh Ghazavi,Farzaneh Ghazavi,Andrica C H de Vries,Henrik Hasle,Veerle Labarque,Riccardo Masetti,Jan Stary,Marry M. van den Heuvel-Eibrink,Jan Philippé,Nadine Van Roy,Yves Benoit,Frank Speleman,Charlotte M. Niemeyer,Christian Flotho,Giuseppe Basso,Geertruy te Kronnie,Pieter Van Vlierberghe,Barbara De Moerloose +24 more
TL;DR: Elevated LIN28B expression was identified as a hallmark of a novel fetal-like subgroup in JMML and gave a biological explanation of why patients with monosomy 7 are rarely diagnosed with high age-adjusted fetal hemoglobin levels.
Journal ArticleDOI
Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
Pedro Henrique Viana Saavedra,Linyan Huang,Linyan Huang,Farzaneh Ghazavi,Stephanie Kourula,Tom Vanden Berghe,Nozomi Takahashi,Peter Vandenabeele,Mohamed Lamkanfi,Mohamed Lamkanfi +9 more
TL;DR: The studies establish that C. difficile enterotoxins induce activation of executioner caspases 3/7 via the intrinsic apoptosis pathway, and demonstrate that caspase-3/7-mediated IEC apoptosis is critical for in vivo host defense during early stages of CDI.
Journal ArticleDOI
Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi,Barbara De Moerloose,Wouter Van Loocke,Annelynn Wallaert,Hetty Helsmoortel,Alina Ferster,Marleen Bakkus,Geneviève Plat,Eric Delabesse,Anne Uyttebroeck,Filip Van Nieuwerburgh,Dieter Deforce,Nadine Van Roy,Frank Speleman,Yves Benoit,Tim Lammens,Pieter Van Vlierberghe +16 more
TL;DR: This study defined a unique lncRNA expression signature associated with ETV6/RUNX1-positive BCP-ALL and identified lnc-RTN4R-1 and lNC-NKX2-3-1 as lncRNAs that might be functionally implicated in the biology of this prevalent subtype of human leukemia.
Journal ArticleDOI
Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia.
Anne Benard-Slagter,Ilse Zondervan,Karel de Groot,Farzaneh Ghazavi,Virinder Kaur Sarhadi,Pieter Van Vlierberghe,Barbara De Moerloose,Claire Schwab,Kim Vettenranta,Christine J. Harrison,Sakari Knuutila,Jan P. Schouten,Tim Lammens,Suvi Savola +13 more
TL;DR: The digitalMLPA assay reliably identified whole chromosome losses and gains, whole gene deletions or gains, intrachromosomal amplification of chromosome 21, fusion genes, and intragenic deletions, which were confirmed by other methods.