A
Alexander R. van Vliet
Researcher at Katholieke Universiteit Leuven
Publications - 24
Citations - 2216
Alexander R. van Vliet is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Unfolded protein response & Endoplasmic reticulum. The author has an hindex of 14, co-authored 20 publications receiving 1600 citations. Previous affiliations of Alexander R. van Vliet include Francis Crick Institute.
Papers
More filters
Journal ArticleDOI
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun,Pieter Mestdagh,Patrizia Agostinis,Özden Akay,Sushma Anand,Jasper Anckaert,Zoraida Andreu Martinez,Tine Baetens,Els Beghein,Laurence Bertier,Geert Berx,Janneke Boere,Stephanie Boukouris,Michel Bremer,Dominik Buschmann,James Brian Byrd,Clara Casert,Lesley Cheng,Anna Cmoch,Delphine Daveloose,Eva De Smedt,Seyma Demirsoy,Victoria Depoorter,Bert Dhondt,Tom A. P. Driedonks,Aleksandra M. Dudek,Abdou ElSharawy,Ilaria Floris,Andrew D Foers,Kathrin Gärtner,Abhishek D. Garg,Edward Geeurickx,Jan Gettemans,Farzaneh Ghazavi,Bernd Giebel,Tom Groot Kormelink,Grace V. Hancock,Hetty Helsmoortel,Andrew F. Hill,Vincent Hyenne,Hina Kalra,David Kim,Joanna Kowal,Joanna Kowal,Sandra Kraemer,Petra Leidinger,Carina Leonelli,Yaxuan Liang,Lien Lippens,Shu Liu,Alessandra Lo Cicero,Alessandra Lo Cicero,Shaun Martin,Suresh Mathivanan,Prabhu Mathiyalagan,Tamás Matusek,Gloria Milani,Marta Monguió-Tortajada,Liselot Mus,Dillon C. Muth,Andrea Németh,Esther N. M. Nolte-‘t Hoen,Lorraine O'Driscoll,Roberta Palmulli,Roberta Palmulli,Michael W. Pfaffl,Bjarke Primdal-Bengtson,Bjarke Primdal-Bengtson,Erminia Romano,Quentin Rousseau,Susmita Sahoo,Natalia G. Sampaio,Monisha Samuel,Benjamin J. Scicluna,Bieke Soen,Anneleen Steels,Johannes V. Swinnen,Maarit Takatalo,Safia Thaminy,Clotilde Théry,Clotilde Théry,Joeri Tulkens,Isabel Van Audenhove,Susanne G. van der Grein,Alan Van Goethem,Martijn J. C. van Herwijnen,Guillaume van Niel,Guillaume van Niel,Nadine Van Roy,Alexander R. van Vliet,Niels Vandamme,Suzanne Vanhauwaert,Glenn Vergauwen,Frederik J. Verweij,Frederik J. Verweij,Annelynn Wallaert,Marca H. M. Wauben,Kenneth W. Witwer,Marijke I. Zonneveld,Olivier De Wever,Jo Vandesompele,An Hendrix +101 more
TL;DR: It is argued that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments and EV-TRACK, a crowdsourcing knowledgebase that centralizes EV biology and methodology, is described.
Journal ArticleDOI
New functions of mitochondria associated membranes in cellular signaling
TL;DR: Besides their established role as a signaling hub for Ca(2+) and lipid transfer between ER and mitochondria, MAMs have been recently shown to regulate mitochondrial shape and motility, energy metabolism and redox status and to be central to the modulation of various key processes like ER stress, autophagy and inflammasome signaling.
Journal ArticleDOI
ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function
Romain Galmes,Audrey Houcine,Alexander R. van Vliet,Patrizia Agostinis,Catherine L. Jackson,Francesca Giordano +5 more
TL;DR: It is shown that, in addition to ER-PM contact sites, ORP5 and ORP8 are also localized to ER–mitochondria contacts and interact with the outer mitochondrial membrane protein PTPIP51.
Journal ArticleDOI
The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.
Alexander R. van Vliet,Francesca Giordano,Sarah Gerlo,Inmaculada Segura,Sofie Van Eygen,Geert Molenberghs,Susana Rocha,Audrey Houcine,Rita Derua,Tom Verfaillie,Jeroen Vangindertael,Herlinde De Keersmaecker,Etienne Waelkens,Jan Tavernier,Johan Hofkens,Wim Annaert,Peter Carmeliet,Afshin Samali,Hideaki Mizuno,Patrizia Agostinis +19 more
TL;DR: Using proximity-dependent biotin identification (BioID), the actin-binding protein Filamin A (FLNA) is identified as a key PERK interactor and an unprecedented role of PERK is unraveled in the regulation of ER-PM appositions through the modulation of theActin cytoskeleton.
Journal ArticleDOI
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
Amado Carreras-Sureda,Fabián Jaña,Hery Urra,Sylvère Durand,Sylvère Durand,David E. Mortenson,Alfredo Sagredo,Galdo Bustos,Galdo Bustos,Younis Hazari,Eva Ramos-Fernández,Maria Livia Sassano,Philippe Pihán,Alexander R. van Vliet,Matías González-Quiroz,Angie K. Torres,Cheril Tapia-Rojas,Martijn Kerkhofs,Rubén Vicente,Randal J. Kaufman,Nibaldo C. Inestrosa,Christian Gonzalez-Billault,Christian Gonzalez-Billault,R. Luke Wiseman,Patrizia Agostinis,Geert Bultynck,Felipe A. Court,Guido Kroemer,J César Cárdenas,Claudio Hetz +29 more
TL;DR: A non-canonical role for IRE1α as a scaffold that stabilizes InsP3Rs at MAMs to control calcium uptake, fine-tunes ER–mitochondrial communication and regulates energy metabolism via AMPK is uncovered.