E
Emmanuel J. Favaloro
Researcher at Westmead Hospital
Publications - 731
Citations - 22370
Emmanuel J. Favaloro is an academic researcher from Westmead Hospital. The author has contributed to research in topics: Von Willebrand disease & Medicine. The author has an hindex of 60, co-authored 648 publications receiving 18261 citations. Previous affiliations of Emmanuel J. Favaloro include University of Verona & University of Sydney.
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Journal ArticleDOI
COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TL;DR: The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.
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Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor
J E Sadler,U. Budde,Jeroen Eikenboom,Emmanuel J. Favaloro,Frank Hill,Lars Holmberg,Jørgen Ingerslev,Christine A. Lee,David Lillicrap,P. M. Mannucci,Claudine Mazurier,Dominique Meyer,William L. Nichols,M. Nishino,Ian R. Peake,F. Rodeghiero,Reinhard Schneppenheim,Zaverio M. Ruggeri,A. Srivastava,Robert R. Montgomery,Augusto B. Federici +20 more
TL;DR: Six categories of von Willebrand disease correlate with important clinical features and therapeutic requirements, and certain VWD types, especially type 1 and type 2A, encompass several pathophysiologic mechanisms that sometimes can be distinguished by appropriate laboratory studies.
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D-dimer is Associated with Severity of Coronavirus Disease 2019: A Pooled Analysis.
TL;DR: It is explored whether increased D-dimer values — which are a frequent occurrence in patients with COVID-19 — may be associated with disease severity.
Journal ArticleDOI
Characterization of GMP-140 (P-selectin) as a circulating plasma protein.
Lindsay Dunlop,Michael P. Skinner,Linda J. Bendall,Emmanuel J. Favaloro,P. A. Castaldi,J J Gorman,Jennifer R. Gamble,Mathew Vadas,Michael C. Berndt +8 more
TL;DR: Since it has been shown that fluid-phase GMP-140 is antiinflammatory and downregulates CD18- dependent neutrophil adhesion and respiratory burst, its presence in plasma may be of major importance in preventing the inadvertent activation of neutrophils in the circulation.
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Hyperinflammation and derangement of renin-angiotensin-aldosterone system in COVID-19: A novel hypothesis for clinically suspected hypercoagulopathy and microvascular immunothrombosis.
TL;DR: The underlying pathogenesis and the interaction between multiple systems, resulting in propagation of immunothrombosis, are discussed and may lead to both an improved understanding of COVID-19 pathophysiology and identification of innovative and efficient therapeutic targets to reverse the otherwise unfavorable clinical outcome of many of these patients.