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Eric H. Davidson
Researcher at California Institute of Technology
Publications - 455
Citations - 49098
Eric H. Davidson is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Gene & Strongylocentrotus purpuratus. The author has an hindex of 106, co-authored 454 publications receiving 47058 citations. Previous affiliations of Eric H. Davidson include Carnegie Institution for Science & Institute for Systems Biology.
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Journal ArticleDOI
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
Amy E. Pasquinelli,Brenda J. Reinhart,Frank J. Slack,Mark Q. Martindale,Mitzi I. Kuroda,Betsy Maller,David C. Hayward,Eldon E. Ball,Bernard M. Degnan,Peter Müller,Jürg Spring,Ashok Srinivasan,Mark C. Fishman,John R. Finnerty,Joseph C. Corbo,Michael P. Levine,Patrick S. Leahy,Eric H. Davidson,Gary Ruvkun +18 more
TL;DR: Two small RNAs regulate the timing of Caenorhabditis elegans development and may control late temporal transitions during development across animal phylogeny.
Journal ArticleDOI
Direct multiplexed measurement of gene expression with color-coded probe pairs.
Gary K. Geiss,Roger E. Bumgarner,Brian Birditt,Timothy Dahl,Naeem Dowidar,Dwayne Dunaway,H Perry Fell,Sean Ferree,Renee D George,Renee D George,Tammy Grogan,Jeffrey J James,Malini Maysuria,Jeffrey D Mitton,Paola Oliveri,Paola Oliveri,Jennifer L Osborn,Jennifer L Osborn,Tao Peng,Amber L Ratcliffe,Philippa J. Webster,Eric H. Davidson,Leroy Hood,Krassen Dimitrov +23 more
TL;DR: NanoString nCounter as mentioned in this paper is a system for gene expression measurement with high multiplex capability and digital readout, which can detect individual mRNA transcripts without enzymatic reactions or bias.
Journal ArticleDOI
Gene Regulation for Higher Cells: A Theory
Roy J. Britten,Eric H. Davidson +1 more
TL;DR: Direct support for the idea that regulation of gene activity underlies cell differentiation comes from evidence that much of the genome in higher cell types is inactive and that different ribonucleic acids are synthesized in different cell types.
Journal ArticleDOI
A Genomic Regulatory Network for Development
Eric H. Davidson,Jonathan P. Rast,Paola Oliveri,Andrew Ransick,Cristina Calestani,Chiou-Hwa Yuh,Takuya Minokawa,Gabriele Amore,Veronica F. Hinman,Cesar Arenas-Mena,Ochan Otim,C. Titus Brown,Carolina B. Livi,Pei Yun Lee,Roger Revilla,Alistair G. Rust,Zheng Jun Pan,Maria J. Schilstra,Peter J.C. Clarke,Maria Ina Arnone,Lee Rowen,R. Andrew Cameron,David R. McClay,Leroy Hood,Hamid Bolouri +24 more
TL;DR: A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here and reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.