E
Etienne Ruppé
Researcher at University of Paris
Publications - 132
Citations - 6433
Etienne Ruppé is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 34, co-authored 112 publications receiving 4277 citations. Previous affiliations of Etienne Ruppé include Université Paris-Saclay & Pasteur Institute.
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Journal ArticleDOI
Protection of the Human Gut Microbiome From Antibiotics.
Jean de Gunzburg,Amine Ghozlane,Annie Ducher,Xavier Duval,Xavier Duval,Etienne Ruppé,Laurence Armand-Lefevre,Laurence Armand-Lefevre,Frédérique Sablier-Gallis,Charles Burdet,Charles Burdet,Loubna Alavoine,Elisabeth Chachaty,Violaine Augustin,Marina Varastet,Florence Levenez,Sean Kennedy,Nicolas Pons,Antoine Andremont,Antoine Andremont +19 more
TL;DR: In a phase 1 clinical study, coadministration of the adsorbent-based DAV132 product together with the fluoroquinolone antibiotic moxifloxacin, while not affecting the plasma concentrations of the antibiotic, reduced by >99% exposure of the intestinal microbiota to the moxIFl Oxacin.
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Massive Increase, Spread, and Exchange of Extended Spectrum β-Lactamase–Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger
Paul-Louis Woerther,Cécile Angebault,Hervé Jacquier,Henri-Charles Hugede,Ann-Carole Janssens,Sani Sayadi,Assiya El Mniai,Laurence Armand-Lefevre,Etienne Ruppé,François Barbier,Laurent Raskine,Anne-Laure Page,Nathalie de Rekeneire,Antoine Andremont +13 more
TL;DR: Cross-transmission and high selective pressure lead to very high acquisition of ESBL-E carriage, contributing to dissemination in the community and strict hygiene measures as well as careful balancing of benefit-risk ratio of current antibiotic policies need to be reevaluated.
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In-depth resistome analysis by targeted metagenomics
Val F. Lanza,Fernando Baquero,José L. Martínez,Ricardo Ramos-Ruiz,Bruno Gonzalez-Zorn,Antoine Andremont,Antonio Sánchez-Valenzuela,Dusko Ehrlich,Dusko Ehrlich,Sean Kennedy,Sean Kennedy,Etienne Ruppé,Etienne Ruppé,Willem van Schaik,Willem van Schaik,Rob J. L. Willems,Fernando de la Cruz,Fernando de la Cruz,Teresa M. Coque +18 more
TL;DR: ResCap, the first targeted sequence capture platform specifically developed to analyze resistomes, greatly enhances the sensitivity and specificity of available metagenomic methods and offers the possibility to analyze genes related to the selection and transfer of antimicrobial resistance (biocides, heavy metals, plasmids).
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Relative Fecal Abundance of Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains and Their Occurrence in Urinary Tract Infections in Women
Etienne Ruppé,Brandusa Elena Lixandru Lixandru,Radu Cojocaru,Cagri Buke,Elisabeth Paramythiotou,Cécile Angebault,Claire Visseaux,Ingrid Cecile Djuikoue,Esra Erdem,Olga Burduniuc,Assiya El Mniai,Candice Marcel,Marion Perrier,Thomas Kesteman,Olivier Clermont,Erick Denamur,Laurence Armand-Lefevre,Antoine Andremont +17 more
TL;DR: In conclusion, ESBL-RA was linked to the occurrence of ESBL E. coli UTI in women who were not exposed to antibiotics and who had the same clone of E. bacteria in urine samples and fecal samples.
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High prevalence of the arginine catabolic mobile element in carriage isolates of methicillin-resistant Staphylococcus epidermidis
François Barbier,David Lebeaux,David Hernandez,Anne-Sophie Delannoy,Valérie Caro,Patrice Francois,Jacques Schrenzel,Etienne Ruppé,Kevin Gaillard,Michel Wolff,Sylvain Brisse,Antoine Andremont,Raymond Ruimy +12 more
TL;DR: ACME is widely disseminated in MRSE strains colonizing outpatients and may contribute to their spread in a community environment with low antibiotic exposure, as suggested for USA300.