Eve McLoughlin

TL;DR: In this paper, the authors explored a specific phenotype of COVID-19-associated hyperinflammation (COV-HI), and its associations with escalation of respiratory support and survival.

TL;DR: In children with CKD without concomitant disease affecting HDL function, HDL dysfunction begins in early CKD, progressing as renal function declines, and is partially reversed after kidney transplantation.

TL;DR: It is demonstrated that even minor alterations in systemic inflammation can impair the endothelial protective effects of HDL, and this findings suggest that HDL dysfunction may represent a novel mechanism linking inflammation with progression of atheroma.

TL;DR: The M+I combination was superior to the M+P alone, suggesting that the tumour necrosis factor-α pathway may have a role in HDL vascular properties, which can be improved with anti-inflammatory treatment in patients with RA.

TL;DR: Increased levels of HDL-c commonly observed in individuals with Type 1 diabetes may be detrimental to endothelial function when accompanied by renal dysfunction and chronic inflammation.