F
Fabiola Olivieri
Researcher at Marche Polytechnic University
Publications - 246
Citations - 18531
Fabiola Olivieri is an academic researcher from Marche Polytechnic University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 56, co-authored 214 publications receiving 15697 citations. Previous affiliations of Fabiola Olivieri include University of Bologna & Advanced Technology Center.
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Journal ArticleDOI
Inflamm‐aging: An Evolutionary Perspective on Immunosenescence
Claudio Franceschi,Massimiliano Bonafè,Silvana Valensin,Fabiola Olivieri,Maria De Luca,Enzo Ottaviani,Giovanna De Benedictis +6 more
TL;DR: The beneficial effects of inflammation devoted to the neutralization of dangerous/harmful agents early in life and in adulthood become detrimental late in life in a period largely not foreseen by evolution, according to the antagonistic pleiotropy theory of aging.
Journal ArticleDOI
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
Claudio Franceschi,Miriam Capri,Daniela Monti,Sergio Giunta,Fabiola Olivieri,Federica Sevini,Maria Panagiota Panourgia,Laura Invidia,Laura Celani,Maria Scurti,Elisa Cevenini,Gastone Castellani,Stefano Salvioli +12 more
TL;DR: It is proposed that inflammaging can be flanked by anti-inflammaging as major determinants not only of immunosenescence but eventually of global aging and longevity.
Journal ArticleDOI
Human polymorphism at microRNAs and microRNA target sites.
Liuqing Yang,Chunru Lin,Chunyu Jin,Joy C. Yang,Bogdan Tanasa,Wenbo Wen-Hsiung Li,Daria Merkurjev,Kenneth a. Ohgi,Jie Zhang,Christopher P. Evans,Michael G. Rosenfeld,Charles E Vejnar,Matthias Blum,Evgeny M. Zdobnov,A Turchinovich,T R Samatov,a G Tonevitsky,B Burwinkel,Georg Schett,Dirk Elewaut,Iain B McInnes,Jean-Michel Dayer,Markus F Neurath,Sachin Pundhir,Jan Gorodkin,Fabiola Olivieri,Maria Rita Rippo,Antonio Domenico Procopio,Francesca Fazioli,Lukas T Jeker,Xuyu Zhou,Robert Blelloch,Jeffrey a Bluestone,Claudiane Guay,Romano Regazzi,Roopali Gandhi,Brian Healy,Taha Gholipour,Svetlana Egorova,Alexander Musallam,Mohammad Shuja Hussain,Parham Nejad,Bonny Patel,Hillary Hei,Samia Khoury,Francisco Quintana,Pia Kivisakk,Tanuja Chitnis,Howard L Weiner,Yun Deng,Jian Zhao,Daisuke Sakurai,Kenneth M. Kaufman,Jeffrey C. Edberg,Robert P. Kimberly,Diane L. Kamen,Gary S. Gilkeson,Chaim O. Jacob,R. Hal Scofield,Carl D. Langefeld,Jennifer A. Kelly,Rosalind Ramsey-Goldman,Michelle Petri,John D. Reveille,Luis M. Vilá,Graciela S. Alarcón,Timothy J. Vyse,Bernardo A. Pons-Estel,Barry I. Freedman,Patrick M. Gaffney,Kathy Moser Sivils,Judith A. James,Peter K. Gregersen,Juan-Manuel Anaya,Timothy B. Niewold,Joan T. Merrill,Lindsey A. Criswell,Anne M. Stevens,Susan A. Boackle,Rita M. Cantor,Weiling Chen,J Grossman,Bevra H. Hahn,John B. Harley,Marta E Alarcόn-Riquelme,Elizabeth E. Brown,Betty P. Tsao,Susan Carpenter,Maninjay Atianand,Daniel Aiello,Emiliano P Ricci,Pallavi Gandhi,Lisa L Hall,Meg Byron,Brian Monks,Meabh Henry-Bezy,Jeanne B Lawrence,Luke a J O'Neill,Melissa J Moore,Daniel R Caffrey,Katherine a Fitzgerald,Dan-Xia Zhu,Lei Fan,Rui-Nan Lu,Cheng Fang,Wen-Yi Shen,Zhi-Jian Zou,Yin-Hua Wang,Hua-Yuan Zhu,Kou-Rong Miao,Peng Liu,Wei Xu,Jian-Yong Li,Jing Gong,Yin Tong,Hong-Mei Zhang,Kai Wang,Tao Hu,Ge Shan,Jun Sun,An-Yuan Guo,V Davalos,C Moutinho,A Villanueva,R Boque,Pedro Silva,F Carneiro,M Esteller,R Stephanie Huang,Eric R. Gamazon,Dana Ziliak,Yujia Wen,Hae Kyung Im,Wei Zhang,Claudia Wing,Shiwei Duan,Wasim K Bleibel,Nancy J. Cox,M. Eileen Dolan,Patrick Brest,Pierre Lapaquette,Mouloud Souidi,Kevin Lebrigand,Annabelle Cesaro,Valérie Vouret-Craviari,Bernard Mari,Pascal Barbry,Jean-François Mosnier,Xavier Hébuterne,Annick Harel-Bellan,Baharia Mograbi,Arlette Darfeuille-Michaud,Paul Hofman,Jonathan Marchini,Bryan Howie,Lucia A. Hindorff,Praveen Sethupathy,Heather a Junkins,Erin M. Ramos,Jayashri P Mehta,Francis S. Collins,Teri A. Manolio,William O.C.M. Cookson,Liming Liang,Gonçalo R. Abecasis,Miriam F. Moffatt,Mark Lathrop,Matthew A. Saunders,Han Liang +168 more
Journal ArticleDOI
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.
Massimiliano Bonafè,Michelangela Barbieri,Francesca Marchegiani,Fabiola Olivieri,Emilia Ragno,Emilia Ragno,Claudia Giampieri,Elena Mugianesi,Matteo Centurelli,Claudio Franceschi,G. Paolisso,G. Paolisso +11 more
TL;DR: The findings of this investigation represent the first indication that free IGF-I plasma levels and human longevity are coregulated by an overlapping set of genes, contributing to the hypothesis that the impact of the IGF- I/insulin pathway on longevity is a property that has been evolutionarily conserved throughout the animal kingdom.
Journal ArticleDOI
A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity.
Massimiliano Bonafè,Fabiola Olivieri,Luca Cavallone,Simona Giovagnetti,Francesca Marchegiani,Maurizio Cardelli,Carlo Pieri,Maurizio Marra,Roberto Antonicelli,Rosmarie Lisa,Maria Rosaria Rizzo,Giuseppe Paolisso,Daniela Monti,Claudio Franceschi,Claudio Franceschi +14 more
TL;DR: The data suggest that those individuals who are genetically predisposed to produce high levels of IL‐6 during aging, i.e. –174 locus GG homozygous men, are disadvantaged for longevity.