M
Miriam F. Moffatt
Researcher at National Institutes of Health
Publications - 202
Citations - 27089
Miriam F. Moffatt is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 62, co-authored 186 publications receiving 24097 citations. Previous affiliations of Miriam F. Moffatt include Imperial College London & National Institute for Health Research.
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Genetic studies of body mass index yield new insights for obesity biology
Adam E. Locke,Bratati Kahali,Sonja I. Berndt,Anne E. Justice,Tune H. Pers,Felix R. Day,Corey Powell,Sailaja Vedantam,Martin L. Buchkovich,Jian Yang,Damien C. Croteau-Chonka,Tõnu Esko,Tove Fall,Teresa Ferreira,Stefan Gustafsson,Zoltán Kutalik,Jian'an Luan,Reedik Mägi,Joshua C. Randall,Thomas W. Winkler,Andrew R. Wood,Tsegaselassie Workalemahu,Jessica D. Faul,Jennifer A. Smith,Jing Hua Zhao,Wei Zhao,Jin Chen,Rudolf S N Fehrmann,Åsa K. Hedman,Juha Karjalainen,Ellen M. Schmidt,Devin Absher,Najaf Amin,Denise Anderson,Marian Beekman,Jennifer L. Bolton,Jennifer L. Bragg-Gresham,Steven Buyske,Ayse Demirkan,Guohong Deng,Georg Ehret,Bjarke Feenstra,Mary F. Feitosa,Krista Fischer,Anuj Goel,Jian Gong,Anne U. Jackson,Stavroula Kanoni,Marcus E. Kleber,Kati Kristiansson,Unhee Lim,Vaneet Lotay,Massimo Mangino,Irene Mateo Leach,Carolina Medina-Gomez,Sarah E. Medland,Mike A. Nalls,Cameron D. Palmer,Dorota Pasko,Sonali Pechlivanis,Marjolein Peters,Inga Prokopenko,Dmitry Shungin,Alena Stančáková,Rona J. Strawbridge,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Zhaoming Wang,Loic Yengo,Weihua Zhang,Aaron Isaacs,Eva Albrecht,Johan Ärnlöv,Gillian M. Arscott,Antony P. Attwood,Stefania Bandinelli,Amy Barrett,Isabelita Bas,Claire Bellis,Amanda J. Bennett,Christian Berne,Roza Blagieva,Matthias Blüher,Stefan Böhringer,Lori L. Bonnycastle,Yvonne Böttcher,Heather A. Boyd,Marcel Bruinenberg,Ida Henriette Caspersen,Yii-Der Ida Chen,Robert Clarke,E. Warwick Daw,Anton J. M. de Craen,Graciela E. Delgado,Maria Dimitriou,Alex S. F. Doney,Niina Eklund,Karol Estrada,Elodie Eury,Lasse Folkersen,Ross M. Fraser,Melissa E. Garcia,Frank Geller,Vilmantas Giedraitis,Bruna Gigante,Alan S. Go,Alain Golay,Alison H. Goodall,Scott D. Gordon,Mathias Gorski,Hans-Jörgen Grabe,Harald Grallert,Tanja B. Grammer,Jürgen Gräßler,Henrik Grönberg,Christopher J. Groves,Gaëlle Gusto,Jeffrey Haessler,Per Hall,Toomas Haller,Göran Hallmans,Catharina A. Hartman,Maija Hassinen,Caroline Hayward,Nancy L. Heard-Costa,Quinta Helmer,Christian Hengstenberg,Oddgeir L. Holmen,Jouke-Jan Hottenga,Alan James,Janina M. Jeff,Åsa Johansson,Jennifer Jolley,Thorhildur Juliusdottir,Leena Kinnunen,Wolfgang Koenig,Markku Koskenvuo,Wolfgang Kratzer,Jaana Laitinen,Claudia Lamina,Karin Leander,Nanette R. Lee,Peter Lichtner,Lars Lind,Jaana Lindström,Ken Sin Lo,Stéphane Lobbens,Roberto Lorbeer,Yingchang Lu,François Mach,Patrik K. E. Magnusson,Anubha Mahajan,Wendy L. McArdle,Stela McLachlan,Cristina Menni,Sigrun Merger,Evelin Mihailov,Lili Milani,Alireza Moayyeri,Keri L. Monda,Mario A. Morken,Antonella Mulas,Gabriele Müller,Martina Müller-Nurasyid,Arthur W. Musk,Ramaiah Nagaraja,Markus M. Nöthen,Ilja M. Nolte,Stefan Pilz,Nigel W. Rayner,Frida Renström,Rainer Rettig,Janina S. Ried,Stephan Ripke,Neil R. Robertson,Lynda M. Rose,Serena Sanna,Hubert Scharnagl,Salome Scholtens,Fredrick R. Schumacher,William R. Scott,Thomas Seufferlein,Jianxin Shi,Albert V. Smith,Joanna Smolonska,Alice Stanton,Valgerdur Steinthorsdottir,Kathleen Stirrups,Heather M. Stringham,Johan Sundström,Morris A. Swertz,Amy J. Swift,Ann-Christine Syvänen,Sian-Tsung Tan,Bamidele O. Tayo,Barbara Thorand,Gudmar Thorleifsson,Jonathan Tyrer,Hae-Won Uh,Liesbeth Vandenput,Frank C. Verhulst,Sita H. Vermeulen,Niek Verweij,Judith M. Vonk,Lindsay L. Waite,Helen R. Warren,Dawn M. Waterworth,Michael N. Weedon,Lynne R. Wilkens,Christina Willenborg,Tom Wilsgaard,Mary K. Wojczynski,Andrew Wong,Alan F. Wright,Qunyuan Zhang,Eoin P. Brennan,Murim Choi,Zari Dastani,Alexander W. Drong,Per Eriksson,Anders Franco-Cereceda,Jesper R. Gådin,Ali G. Gharavi,Michael E. Goddard,Robert E. Handsaker,Jinyan Huang,Fredrik Karpe,Sekar Kathiresan,Sarah Keildson,Krzysztof Kiryluk,Michiaki Kubo,Jong-Young Lee,Liming Liang,Richard P. Lifton,Baoshan Ma,Steven A. McCarroll,Amy Jayne McKnight,Josine L. Min,Miriam F. Moffatt,Grant W. Montgomery,Joanne M. Murabito,George Nicholson,Dale R. Nyholt,Yukinori Okada,John R. B. Perry,Rajkumar Dorajoo,Eva Reinmaa,Rany M. Salem,Niina Sandholm,Robert A. Scott,Lisette Stolk,Atsushi Takahashi,Toshihiro Tanaka,Ferdinand M. van't Hooft,Anna A. E. Vinkhuyzen,Harm-Jan Westra,Wei Zheng,Krina T. Zondervan,Andrew C. Heath,Dominique Arveiler,Stephan J. L. Bakker,John Beilby,Richard N. Bergman,John Blangero,Pascal Bovet,Harry Campbell,Mark J. Caulfield,Giancarlo Cesana,Aravinda Chakravarti,Daniel I. Chasman,Peter S. Chines,Francis S. Collins,Dana C. Crawford,L. Adrienne Cupples,Daniele Cusi,John Danesh,Ulf de Faire,Hester M. den Ruijter,Anna F. Dominiczak,Raimund Erbel,Jeanette Erdmann,Johan G. Eriksson,Martin Farrall,Stephan B. Felix,Ele Ferrannini,Jean Ferrières,Ian Ford,Nita G. Forouhi,Terrence Forrester,Oscar H. Franco,Ron T. Gansevoort,Pablo V. Gejman,Christian Gieger,Omri Gottesman,Vilmundur Gudnason,Ulf Gyllensten,Alistair S. Hall,Tamara B. Harris,Andrew T. Hattersley,Andrew A. Hicks,Lucia A. Hindorff,Aroon D. Hingorani,Albert Hofman,Georg Homuth,G. Kees Hovingh,Steve E. Humphries,Steven C. Hunt,Elina Hyppönen,Thomas Illig,Kevin B. Jacobs,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Berit Johansen,Pekka Jousilahti,J. Wouter Jukema,Antti Jula,Jaakko Kaprio,John J.P. Kastelein,Sirkka Keinänen-Kiukaanniemi,Lambertus A. Kiemeney,Paul Knekt,Jaspal S. Kooner,Charles Kooperberg,Peter Kovacs,Aldi T. Kraja,Meena Kumari,Johanna Kuusisto,Timo A. Lakka,Claudia Langenberg,Loic Le Marchand,Terho Lehtimäki,Valeriya Lyssenko,Satu Männistö,André Marette,Tara C. Matise,Colin A. McKenzie,Barbara McKnight,Frans L. Moll,Andrew D. Morris,Andrew P. Morris,Jeffrey C. Murray,Mari Nelis,Claes Ohlsson,Albertine J. Oldehinkel,Ken K. Ong,Pamela A. F. Madden,Gerard Pasterkamp,John F. Peden,Annette Peters,Dirkje S. Postma,Peter P. Pramstaller,Jackie F. Price,Lu Qi,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Treva Rice,Paul M. Ridker,John D. Rioux,Marylyn D. Ritchie,Igor Rudan,Veikko Salomaa,Nilesh J. Samani,Jouko Saramies,Mark A. Sarzynski,Heribert Schunkert,Peter Schwarz,Peter S. Sever,Alan R. Shuldiner,Juha Sinisalo,Ronald P. Stolk,Konstantin Strauch,Anke Tönjes,David-Alexandre Trégouët,Angelo Tremblay,Elena Tremoli,Jarmo Virtamo,Marie-Claude Vohl,Uwe Völker,Gérard Waeber,Gonneke Willemsen,Jacqueline C. M. Witteman,M. Carola Zillikens,Linda S. Adair,Philippe Amouyel,Folkert W. Asselbergs,Themistocles L. Assimes,Murielle Bochud,Bernhard O. Boehm,Eric Boerwinkle,Stefan R. Bornstein,Erwin P. Bottinger,Claude Bouchard,Stéphane Cauchi,John C. Chambers,Stephen J. Chanock,Richard S. Cooper,Paul I.W. de Bakker,George Dedoussis,Luigi Ferrucci,Paul W. Franks,Philippe Froguel,Leif Groop,Christopher A. Haiman,Anders Hamsten,Jennie Hui,David J. Hunter,Kristian Hveem,Robert C. Kaplan,Mika Kivimäki,Diana Kuh,Markku Laakso,Yongmei Liu,Nicholas G. Martin,Winfried März,Mads Melbye,Andres Metspalu,Susanne Moebus,Patricia B. Munroe,Inger Njølstad,Ben A. Oostra,Colin N. A. Palmer,Nancy L. Pedersen,Markus Perola,Louis Pérusse,Ulrike Peters,Chris Power,Thomas Quertermous,Rainer Rauramaa,Fernando Rivadeneira,Timo Saaristo,Danish Saleheen,Naveed Sattar,Eric E. Schadt,David Schlessinger,P. Eline Slagboom,Harold Snieder,Tim D. Spector,Unnur Thorsteinsdottir,Michael Stumvoll,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,Pim van der Harst,Mark Walker,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,David R. Weir,H-Erich Wichmann,James F. Wilson,Pieter Zanen,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Iris M. Heid,Jeffrey R. O'Connell,David P. Strachan,Kari Stefansson,Cornelia M. van Duijn,Gonçalo R. Abecasis,Lude Franke,Timothy M. Frayling,Mark I. McCarthy,Peter M. Visscher,André Scherag,Cristen J. Willer,Michael Boehnke,Karen L. Mohlke,Cecilia M. Lindgren,Jacques S. Beckmann,Inês Barroso,Kari E. North,Erik Ingelsson,Joel N. Hirschhorn,Ruth J. F. Loos,Elizabeth K. Speliotes +481 more
TL;DR: This paper conducted a genome-wide association study and meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals.
Journal ArticleDOI
A large-scale, consortium-based genomewide association study of asthma.
Miriam F. Moffatt,Ivo Gut,Florence Demenais,David P. Strachan,Emmanuelle Bouzigon,Simon Heath,Erika von Mutius,Martin Farrall,Mark Lathrop,William O.C.M. Cookson +9 more
TL;DR: A few common alleles are associated with disease risk at all ages and suggest a role for communication of epithelial damage to the adaptive immune system and activation of airway inflammation in asthma.
Journal ArticleDOI
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
Miriam F. Moffatt,Michael Kabesch,Liming Liang,Anna L. Dixon,David P. Strachan,Simon Heath,Martin Depner,Andrea von Berg,Albrecht Bufe,Ernst Rietschel,Andrea Heinzmann,Burkard Simma,Thomas Frischer,Saffron A.G. Willis-Owen,Kenny C. C. Wong,Thomas Illig,Christian Vogelberg,Stephan K. Weiland,Erika von Mutius,Gonçalo R. Abecasis,Martin Farrall,Ivo Gut,G. Mark Lathrop,William O.C.M. Cookson +23 more
TL;DR: The results indicate that genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma.
Journal ArticleDOI
Human polymorphism at microRNAs and microRNA target sites.
Liuqing Yang,Chunru Lin,Chunyu Jin,Joy C. Yang,Bogdan Tanasa,Wenbo Wen-Hsiung Li,Daria Merkurjev,Kenneth a. Ohgi,Jie Zhang,Christopher P. Evans,Michael G. Rosenfeld,Charles E Vejnar,Matthias Blum,Evgeny M. Zdobnov,A Turchinovich,T R Samatov,a G Tonevitsky,B Burwinkel,Georg Schett,Dirk Elewaut,Iain B McInnes,Jean-Michel Dayer,Markus F Neurath,Sachin Pundhir,Jan Gorodkin,Fabiola Olivieri,Maria Rita Rippo,Antonio Domenico Procopio,Francesca Fazioli,Lukas T Jeker,Xuyu Zhou,Robert Blelloch,Jeffrey a Bluestone,Claudiane Guay,Romano Regazzi,Roopali Gandhi,Brian Healy,Taha Gholipour,Svetlana Egorova,Alexander Musallam,Mohammad Shuja Hussain,Parham Nejad,Bonny Patel,Hillary Hei,Samia Khoury,Francisco Quintana,Pia Kivisakk,Tanuja Chitnis,Howard L Weiner,Yun Deng,Jian Zhao,Daisuke Sakurai,Kenneth M. Kaufman,Jeffrey C. Edberg,Robert P. Kimberly,Diane L. Kamen,Gary S. Gilkeson,Chaim O. Jacob,R. Hal Scofield,Carl D. Langefeld,Jennifer A. Kelly,Rosalind Ramsey-Goldman,Michelle Petri,John D. Reveille,Luis M. Vilá,Graciela S. Alarcón,Timothy J. Vyse,Bernardo A. Pons-Estel,Barry I. Freedman,Patrick M. Gaffney,Kathy Moser Sivils,Judith A. James,Peter K. Gregersen,Juan-Manuel Anaya,Timothy B. Niewold,Joan T. Merrill,Lindsey A. Criswell,Anne M. Stevens,Susan A. Boackle,Rita M. Cantor,Weiling Chen,J Grossman,Bevra H. Hahn,John B. Harley,Marta E Alarcόn-Riquelme,Elizabeth E. Brown,Betty P. Tsao,Susan Carpenter,Maninjay Atianand,Daniel Aiello,Emiliano P Ricci,Pallavi Gandhi,Lisa L Hall,Meg Byron,Brian Monks,Meabh Henry-Bezy,Jeanne B Lawrence,Luke a J O'Neill,Melissa J Moore,Daniel R Caffrey,Katherine a Fitzgerald,Dan-Xia Zhu,Lei Fan,Rui-Nan Lu,Cheng Fang,Wen-Yi Shen,Zhi-Jian Zou,Yin-Hua Wang,Hua-Yuan Zhu,Kou-Rong Miao,Peng Liu,Wei Xu,Jian-Yong Li,Jing Gong,Yin Tong,Hong-Mei Zhang,Kai Wang,Tao Hu,Ge Shan,Jun Sun,An-Yuan Guo,V Davalos,C Moutinho,A Villanueva,R Boque,Pedro Silva,F Carneiro,M Esteller,R Stephanie Huang,Eric R. Gamazon,Dana Ziliak,Yujia Wen,Hae Kyung Im,Wei Zhang,Claudia Wing,Shiwei Duan,Wasim K Bleibel,Nancy J. Cox,M. Eileen Dolan,Patrick Brest,Pierre Lapaquette,Mouloud Souidi,Kevin Lebrigand,Annabelle Cesaro,Valérie Vouret-Craviari,Bernard Mari,Pascal Barbry,Jean-François Mosnier,Xavier Hébuterne,Annick Harel-Bellan,Baharia Mograbi,Arlette Darfeuille-Michaud,Paul Hofman,Jonathan Marchini,Bryan Howie,Lucia A. Hindorff,Praveen Sethupathy,Heather a Junkins,Erin M. Ramos,Jayashri P Mehta,Francis S. Collins,Teri A. Manolio,William O.C.M. Cookson,Liming Liang,Gonçalo R. Abecasis,Miriam F. Moffatt,Mark Lathrop,Matthew A. Saunders,Han Liang +168 more
Journal ArticleDOI
Disordered Microbial Communities in Asthmatic Airways
Markus Hilty,Conor Burke,Helder Pedro,Helder Pedro,Paul Cardenas,Andrew Bush,Cara Bossley,Jane C. Davies,Aaron Ervine,Len Poulter,Lior Pachter,Miriam F. Moffatt,William O.C.M. Cookson +12 more
TL;DR: The results show the bronchial tree to contain a characteristic microbiota, and suggest that this microbiota is disturbed in asthmatic airways.