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Weiyang Li
Researcher at South China University of Technology
Publications - 12
Citations - 576
Weiyang Li is an academic researcher from South China University of Technology. The author has contributed to research in topics: Cervical cancer & Gene. The author has an hindex of 6, co-authored 12 publications receiving 457 citations. Previous affiliations of Weiyang Li include Beijing Genomics Institute & Tongji Medical College.
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Journal ArticleDOI
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Zheng Hu,Da Zhu,Wei Wang,Weiyang Li,Wenlong Jia,Xi Zeng,Wencheng Ding,Lan Yu,Xiaoli Wang,Liming Wang,Hui Shen,Changlin Zhang,Hongjie Liu,Xiao Liu,Yi Zhao,Xiaodong Fang,Shuai Cheng Li,Wei Chen,Tang Tang,Aisi Fu,Zou Wang,Gang Chen,Qinglei Gao,Shuang Li,Ling Xi,Changyu Wang,Shujie Liao,Xiangyi Ma,Peng Wu,Kezhen Li,Shixuan Wang,Jianfeng Zhou,Wang Jun,Xun Xu,Hui Wang,Ding Ma +35 more
TL;DR: Microhomologous sequence between the human and HPV genomes was significantly enriched near integration breakpoints, indicating that fusion between viral and human DNA may have occurred by microhomology-mediated DNA repair pathways.
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HIVID: An efficient method to detect HBV integration using low coverage sequencing
Weiyang Li,Xi Zeng,Nikki P. Lee,Xiao Liu,Shengpei Chen,Bing Guo,Yi Shang,Xuehan Zhuang,Fang Chen,Guan Wang,Ronnie T.P. Poon,Sheung Tat Fan,Mao Mao,Yingrui Li,Songgang Li,Jun Wang,JianWang,Xun Xu,Hui Jiang,Xiuqing Zhang +19 more
TL;DR: HIVID is a cost-effective methodology with high specificity and sensitivity to identify viral integration in human genome and is compared with that of whole genome sequencing method (WGS).
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An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing.
Hongzhi Cao,Jinghua Wu,Yu Wang,Hui Jiang,Tao Zhang,Xiao Liu,Yinyin Xu,Dequan Liang,Peng Gao,Yepeng Sun,Benjamin Gifford,Mark D'Ascenzo,Xiaomin Liu,Laurent C. A. M. Tellier,Fang Yang,Xin Tong,Dan Chen,Jing Zheng,Weiyang Li,Todd Richmond,Xun Xu,Jun Wang,Yingrui Li +22 more
TL;DR: A cost-effective and highly accurate approach for variant detection and HLA typing in the MHC region is presented, which may lend further insight into immune-mediated diseases studies, and may find clinical utility in transplantation medicine research.
Journal ArticleDOI
Detection and analysis of human papillomavirus (HPV) DNA in breast cancer patients by an effective method of HPV capture.
Ting Wang,Xi Zeng,Weiyang Li,Haijun Zhu,Guan Wang,Xiao Liu,Yonggang Lv,Jinghua Wu,Xuehan Zhuang,Juliang Zhang,Yi Zhao,Haodong Huang,Jing Fan,Qing Yao,Chenyang He,Xiuqing Zhang,Chen Huang,Jianghao Chen,Ling Wang +18 more
TL;DR: This study not only provided an efficient method to capture HPV DNA, but detected the SNVS, coverage, SNV type and depth, and has provided further clue of association between HPV16 and breast cancer.
Journal ArticleDOI
The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
Xin Zhao,Xin Zhao,Xiaomin Liu,Zhang Aiping,Huashuai Chen,Huashuai Chen,Huashuai Chen,Qing Huo,Weiyang Li,Rui Ye,Zhihua Chen,Liping Liang,Qiong A. Liu,Juan Shen,Xin Jin,Wenwen Li,Marianne Nygaard,Xiao Liu,Yong Hou,Ting Ni,Lars Bolund,William K. Gottschalk,Wei Tao,Jun Gu,Xiao-Li Tian,Huanming Yang,Jian Wang,Xun Xu,Michael W. Lutz,Junxia Min,Yi Zeng,Yi Zeng,Chao Nie +32 more
TL;DR: This study investigates the association of CNVs with longevity by comparing the Han Chinese genomes of long-lived individuals from 90 to 117 years of age and the middle-aged from 30 to 65 and identifies eleven CNVs that strongly associate with longevity.