F
Fang Zheng
Researcher at Xi'an Jiaotong University
Publications - 23
Citations - 890
Fang Zheng is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Arthritis & Medicine. The author has an hindex of 10, co-authored 17 publications receiving 674 citations. Previous affiliations of Fang Zheng include Vrije Universiteit Brussel.
Papers
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Journal ArticleDOI
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Charlotte L. Scott,Fang Zheng,Fang Zheng,Patrick De Baetselier,Liesbet Martens,Yvan Saeys,Sofie De Prijck,Saskia Lippens,Chloé Abels,Steve Schoonooghe,Geert Raes,Nick Devoogdt,Bart N. Lambrecht,Alain Beschin,Martin Guilliams +14 more
TL;DR: It is shown that circulating monocytes engraft in the liver, gradually adopt the transcriptional profile of their depleted counterparts and become long-lived self-renewing cells, like embryonic precursors if the niche is available to them.
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Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
Liesu Meng,Wenhua Zhu,Congshan Jiang,Xiaojing He,Weikun Hou,Fang Zheng,Rikard Holmdahl,Shemin Lu +7 more
TL;DR: In this paper, the authors identify the key TLR in pristane-induced arthritis (PIA), a rat model for RA, and to clarify its roles in the initiation and maintenance of arthritis.
Journal ArticleDOI
Molecular Imaging with Macrophage CRIg-Targeting Nanobodies for Early and Preclinical Diagnosis in a Mouse Model of Rheumatoid Arthritis
Fang Zheng,Stéphanie Put,Luc Bouwens,Tony Lahoutte,Patrick Matthys,Serge Muyldermans,Patrick De Baetselier,Nick Devoogdt,Geert Raes,Steve Schoonooghe +9 more
TL;DR: SPECT/CT imaging with 99mTc-NbV4m119 visualizes joint inflammation in CIA, and imaging of joint inflammation with CRIg-specific Nanobodies offers perspectives for clinical applications in RA patients.
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Analysis of correlation between blood biochemical indicators and bone mineral density of post-menopausal women
Shun-zhi Liu,Lifang Tian,Peng Xu,Gui-hua Zhuang,Fang Zheng,Juan Tian,Qi-Lan Ning,Bofeng Zhu,Shemin Lu,Hong Yan +9 more
TL;DR: The purpose of this study was to investigate the significance of sex hormones and some biochemical indicators related to bone metabolism in the genesis and development of osteoporosis and to verify the correlations between the indicators and BMD.
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Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis
Fang Zheng,Amanda Sparkes,Patrick De Baetselier,Steve Schoonooghe,Benoit Stijlemans,Serge Muyldermans,Véronique Flamand,Jo A. Van Ginderachter,Nick N. Devoogdt,Geert Raes,Alain Beschin +10 more
TL;DR: Anti-Clec4F and anti-Vsig4 Nbs targeting KCs as molecular imaging biomarkers could allow non-invasive monitoring/staging of liver pathogenesis.