F
Fanny Guzmán
Researcher at Pontifical Catholic University of Valparaíso
Publications - 164
Citations - 2874
Fanny Guzmán is an academic researcher from Pontifical Catholic University of Valparaíso. The author has contributed to research in topics: Peptide & Epitope. The author has an hindex of 28, co-authored 138 publications receiving 2328 citations. Previous affiliations of Fanny Guzmán include Valparaiso University & Sao Paulo State University.
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Journal ArticleDOI
Peptide synthesis: chemical or enzymatic
TL;DR: The combination of chemical and enzymatic synthesis of peptides with proteolytic enzymes is probably the way to go, since the good properties of each technology can be synergistically used in the context of one process objective.
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Antimicrobial peptides: promising compounds against pathogenic microorganisms.
TL;DR: This review is focused on antibacterial (against Gram (-) and Gram (+) bacteria) and antifungal peptides, discussing action mode of AMPs, and recent advances in the study of the molecular basis of their anti-microbial activity.
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Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21.
Oscar Kashala,Roberto Amador,M. Valero,Alberto Moreno,Arnoldo Barbosa,Beatrice Nickel,Claudia Daubenberger,Fanny Guzmán,Gerd Pluschke,Manuel E. Patarroyo +9 more
TL;DR: It is demonstrated that the use of QS-21 can substantially enhance the immunogenicity of peptide vaccines, such as SPf66, which has been found to induce only CD4+ T cell response, and exhibited the potential to also elicit SPf 66-specific CD8+ responses.
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Immunodiagnosis of parasitic diseases with synthetic peptides.
TL;DR: The concept of multidiagnosis with synthetic peptides, using a novel multi-dot blot assay is introduced and this strategy is cheaper, simpler, reproducible, useful for large scale testing and in most cases, specific and sensitive.
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Antigenicity of the Leishmania infantum histones H2B and H4 during canine viscerocutaneous leishmaniasis
Manuel Soto,Jose M. Requena,Luis Quijada,M J Perez,C.G. Nieto,Fanny Guzmán,Manuel E. Patarroyo,Carlos Alonso +7 more
TL;DR: It is shown that sera from dogs naturally infected with Leishmania infantum contain antibodies that specifically react against the parasite H2B and H4 histones, and the main linear antigenic determinants are located in the amino‐terminal domains of these histones.