F
Fernando Pelaez
Researcher at Merck & Co.
Publications - 124
Citations - 7806
Fernando Pelaez is an academic researcher from Merck & Co.. The author has contributed to research in topics: Integrase & Farnesyl Protein Transferase. The author has an hindex of 41, co-authored 124 publications receiving 7350 citations. Previous affiliations of Fernando Pelaez include Autonomous University of Madrid.
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Journal ArticleDOI
Distribution of the antifungal agents sordarins across filamentous fungi
Francisca Vicente,Angela Basilio,Gonzalo Platas,Javier Collado,Gerald F. Bills,Antonio González del Val,Jesús Martín,José R. Tormo,Guy H. Harris,Deborah L. Zink,Michael C. Justice,Jennifer Nielsen Kahn,Fernando Pelaez +12 more
TL;DR: The production of sordarin is a trait more frequently associated to members of the Xylariales than to any other fungal order, and it was found that sordarins were the most frequently found compounds in the class.
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Antimicrobial activity of ergokonin A from Trichoderma longibrachiatum.
María Francisca Vicente,Angeles Cabello,Gonzalo Platas,Angela Basilio,Maria Teresa Diez,Sarah Dreikorn,Robert A. Giacobbe,Janet C. Onishi,Maria S. Meinz,Myra B. Kurtz,Mark Rosenbach,John R. Thompson,George K. Abruzzo,Amy M. Flattery,Leopold Kong,A. Tsipouras,Kenneth E. Wilson,Fernando Pelaez +17 more
TL;DR: Natural fungal products were screened for antifungal compounds and the mode of action of one of the hits found and the taxonomy of the producing organism were analysed.
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ITS sequencing support for Epicoccum nigrum and Phoma epicoccina being the same biological species.
TL;DR: The phylogenetic relationship between Epicoccum nigrum and Phoma epicoccina has been assessed by means of sequencing of the ITS regions of rDNA and suggests that both entities represent the same biological species.
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Isolation and structure determination of pycnidione, a novel bistropolone stromelysin inhibitor from a Phoma sp.
Guy H. Harris,Karst Hoogsteen,Keith C. Silverman,Susan L. Raghoobar,Gerald F. Bills,Russell B. Lingham,Jack L. Smith,Harry W. Dougherty,Carmen Cascales,Fernando Pelaez +9 more
TL;DR: In this article, a novel bistropolone, pycnidione (1), was isolated by bioassay guided fractionation from fermentations of a Phoma sp., the structure was determined by spectroscopic methods and single crystal X-ray diffraction.
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Tremorgenic mycotoxins, paspalitrem A and C, from a tropical Phomopsis
TL;DR: An endophytic Phomopsis sp.