F
Filip K. Knop
Researcher at University of Copenhagen
Publications - 523
Citations - 17834
Filip K. Knop is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 61, co-authored 437 publications receiving 13614 citations. Previous affiliations of Filip K. Knop include Copenhagen University Hospital & Victor Chang Cardiac Research Institute.
Papers
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Journal ArticleDOI
Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass – a 2-year follow-up
Märta Kristina Borghede,Lars Vinter-Jensen,Henrik Højgaard Rasmussen,Simon Veedfald,Jens F. Rehfeld,Bolette Hartmann,Jens J. Holst,Filip K. Knop,David P. Sonne +8 more
TL;DR: Postprandial enteropancreatic hormonal responses and metabolites in a 22‐year‐old nondiabetic woman with a history of RYGB experiencing severe internal herniation with widespread bowel necrosis were determined.
Journal ArticleDOI
GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D.
Sebastian M. Nguyen Heimbürger,Bjørn Hoe,Chris N. Nielsen,Natasha Chidekel Bergman,Kirsa Skov-Jeppesen,Bolette Hartmann,Jens J. Holst,Flemming Dela,J. Overgaard,Joachim Størling,Tina Vilsbøll,Thomas F. Dejgaard,Jesper F. Havelund,Vladimir Gorshkov,Frank Kjeldsen,Nils J. Færgeman,Martin R. Madsen,Mikkel B. Christensen,Filip K. Knop +18 more
TL;DR: GIP infusion in men with type 1 diabetes transiently decreased bone resorption and increased NEFA and β-oxidation, and hepatic fat content, and supraclavicular skin temperature were increased without affecting WAT transcriptomics, the circulating proteome, lipids, or inflammatory markers.
Journal ArticleDOI
Premature explantation of an EndoBarrier gastrointestinal liner because of sleeve invagination.
Ulrich Rohde,Cecilie A. Federspiel,Peter Vilmann,Steffen U. Friis,Ebbe Langholz,Tina Vilsbøll,Filip K. Knop +6 more
TL;DR: It is emphasized that patients experiencing epigastric pain, nausea, and/or vomiting beyond the first 2 weeks should be thoroughly examined with regard to the function and location of the device, and upper gastrointestinal endoscopy seems preferable because it allows device explantation, depending on the findings.
Patent
Gip peptide analogues
Alexander Hovard Sparre-Ulrich,Mette M. Rosenkilde,Jens J. Holst,Filip K. Knop,Mikkel B. Christensen,Lærke S. Gasbjerg +5 more
TL;DR: In this paper, glucose-dependent insulinotropic polypeptide (GIP)-derived peptide analogues, for example GIP(3-30), and their use as antagonists of the GIP receptor and for treatment of disorders such as obesity, diabetes mellitus and insulin resistance are presented.
Journal ArticleDOI
GIP(3-30)NH2 - a tool for the study of GIP physiology.
TL;DR: The naturally occurring GIP(3-30)NH2 has turned out to constitute a safe and efficacious GIPR antagonist for rodent and human use, hopefully providing new insights into the physiology of GIP, the pathophysiologic involvement of G IP in several diseases and the therapeutic potential of the G IPR.