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Filip K. Knop

Researcher at University of Copenhagen

Publications -  523
Citations -  17834

Filip K. Knop is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 61, co-authored 437 publications receiving 13614 citations. Previous affiliations of Filip K. Knop include Copenhagen University Hospital & Victor Chang Cardiac Research Institute.

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Species-specific action of (Pro3)GIP – a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors

TL;DR: In this paper, a pharmacological analysis of (Pro3)GIP including interspecies differences between the rodent and human GIP system was conducted, and it was shown that Rodent GIPs are more potent and efficacious at their receptors than humanGIPs.
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Mechanism of Metabolic Advantages After Bariatric Surgery: It’s all gastrointestinal factors versus it’s all food restriction

TL;DR: It is striking that amelioration of hyperglycemia after bariatric surgery occurs within days of the surgery, pointing to immediate, weight loss–independent mechanisms possibly related to surgery-induced changes in food intake, gastrointestinal (GI) anatomy, or transit of nutrients.
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Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism.

TL;DR: A broad-spectrum 4-day antibiotics course with vancomycin, gentamycin and meropenem induced shifts in gut microbiota composition that had no clinically relevant short or long-term effects on metabolic variables in healthy glucose-tolerant males.
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Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion.

TL;DR: The effects of the primary human bile acid, chenodeoxycholic acid (CDCA), and the bile Acid sequestrant (BAS) colesevelam, instilled into the stomach, on plasma levels of glucagon‐like peptide‐1 (GLP‐1), glucose‐dependent insulinotropic polypeptides, glucose, insulin, C‐peptide, glucagon, cholecystokinin and gastrin are evaluated.