F
Filip K. Knop
Researcher at University of Copenhagen
Publications - 523
Citations - 17834
Filip K. Knop is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 61, co-authored 437 publications receiving 13614 citations. Previous affiliations of Filip K. Knop include Copenhagen University Hospital & Victor Chang Cardiac Research Institute.
Papers
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Journal ArticleDOI
Effect of Oxyntomodulin, Glucagon, GLP-1, and Combined Glucagon GLP-1 Infusion on Food Intake, Appetite, and Resting Energy Expenditure
Jonatan I. Bagger,Jens J. Holst,Bolette Hartmann,Birgitte Andersen,Filip K. Knop,Tina Vilsbøll +5 more
TL;DR: The gut hormone, oxyntomodulin, is a proglucagon product with body weight-lowering potential that binds to both the glucagon-like peptide-1 (GLP-1) receptor and the glucagons receptor; however, the mechanism behind the body weight -reducing effect remains elusive.
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GIP(3 - 30)NH 2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Lærke S. Gasbjerg,Mikkel B. Christensen,Bolette Hartmann,Amalie R. Lanng,Alexander Hovard Sparre-Ulrich,Maria Buur Nordskov Gabe,Flemming Dela,Tina Vilsbøll,Jens J. Holst,Mette M. Rosenkilde,Filip K. Knop +10 more
TL;DR: GIP(3-30)NH2 was evaluated with homologous receptor binding and receptor activation (cAMP accumulation) studies at the glucagon-like peptide 1 (GLP-1), GLP-2, glucagon, secretin and growth hormone-releasing hormone (GHRH) receptors as discussed by the authors.
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Incidence and Prognosis of Psoriasis and Psoriatic Arthritis in Patients Undergoing Bariatric Surgery.
Alexander Egeberg,Jens Ahm Sørensen,Gunnar Gislason,Gunnar Gislason,Gunnar Gislason,Filip K. Knop,Lone Skov +6 more
TL;DR: Gastric bypass was associated with a significantly reduced risk and improved prognosis of psoriasis and psoriatic arthritis, whereas gastric banding was not, and this finding may be caused by the postoperative differences in nutrient intake and/or weight loss as well as differences in the secretion of hormones that potentially modulate inflammation.
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Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion.
TL;DR: The role of bile acid sequestrants in the treatment of type 2 diabetes, the possible mechanism of action and the role ofbile acid-induced secretion of GLP1 via activation of TGR5 are discussed.
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Patients with psoriasis are insulin resistant.
TL;DR: Patients with psoriasis were more insulin resistant compared with healthy control subjects, and this supports that Psoriasis may be a prediabetic condition.