F
Filip K. Knop
Researcher at University of Copenhagen
Publications - 523
Citations - 17834
Filip K. Knop is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 61, co-authored 437 publications receiving 13614 citations. Previous affiliations of Filip K. Knop include Copenhagen University Hospital & Victor Chang Cardiac Research Institute.
Papers
More filters
Journal ArticleDOI
Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes
Mikkel B. Christensen,Salvatore Calanna,Alexander Hovard Sparre-Ulrich,Peter Lommer Kristensen,Mette M. Rosenkilde,Jens Faber,Francesco Purrello,Gerrit van Hall,Jens J. Holst,Tina Vilsbøll,Filip K. Knop +10 more
TL;DR: It is suggested that during hypoglycemia in patients with T1DM, exogenous GIP increases glucagon responses during the recovery phase after hypoglycesmia and reduces the need for glucose administration.
Journal ArticleDOI
Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis.
Bo Liang,Magdalena Soka,Alex Hørby Christensen,Morten S. Olesen,Anders Peter Larsen,Anders Peter Larsen,Filip K. Knop,Fan Wang,Jonas B. Nielsen,Martin N. Andersen,David T. Humphreys,Stefan A. Mann,Inken G. Huttner,Jamie I. Vandenberg,Jamie I. Vandenberg,Jesper Hastrup Svendsen,Stig Haunsø,Thomas Preiss,Guiscard Seebohm,Søren-Peter Olesen,Nicole Schmitt,Diane Fatkin,Diane Fatkin,Diane Fatkin +23 more
TL;DR: The findings demonstrate the functional importance of ITASK in the atrium and suggest that inactivation of TASK-1 may have diverse effects on atrial size and electrophysiological properties that can contribute to an arrhythmogenic substrate.
Journal ArticleDOI
Effect of antibiotics on gut microbiota, glucose metabolism and body weight regulation: a review of the literature
TL;DR: Human studies examining the effects of antibiotics on body weight regulation and glucose metabolism are reviewed and whether the observed findings may relate to alterations in the composition and function of the gut microbiota are discussed.
Journal ArticleDOI
Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?
TL;DR: It was shown that bile acid-induced activation of T GR5 results in intestinal secretion of GLP-1 and that enhanced TGR5 signaling improves postprandial glucose tolerance in diet-induced obese mice, and this Perspectives article presents these novel findings in the context of prior studies on nutrient-induced GLP1 secretion.
Journal ArticleDOI
Glucagon-like peptide-1 receptor agonists for antipsychotic-associated cardio-metabolic risk factors: A systematic review and individual participant data meta-analysis.
Dan Siskind,Margaret Hahn,Margaret Hahn,Christoph U. Correll,Christoph U. Correll,Anders Fink-Jensen,Anders Fink-Jensen,Anthony W. Russell,Anthony W. Russell,Nikolaj Bak,Brian V. Broberg,Julie M. Larsen,Julie M. Larsen,Pelle L. Ishøy,Tina Vilsbøll,Filip K. Knop,Steve Kisely,Bjørn H Ebdrup +17 more
TL;DR: To evaluate if glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) reduce antipsychotic‐associated body weight gain in patients with schizophrenia, when compared to controls, GLP‐ 1RAs are used.