F
Fin Stolze Larsen
Researcher at University of Copenhagen
Publications - 161
Citations - 9314
Fin Stolze Larsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Cerebral blood flow & Cerebral perfusion pressure. The author has an hindex of 47, co-authored 153 publications receiving 8279 citations. Previous affiliations of Fin Stolze Larsen include Copenhagen University Hospital & Northwestern University.
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Journal ArticleDOI
Cerebral herniation in patients with acute E liver failure is correlated with arterial ammonia concentration
TL;DR: In ALF in humans, vast amounts of ammonia escape hepatic metabolism, leading to high arterial ammonia concentrations, which in turn is associated with increased cerebral ammonia uptake and CH.
Journal ArticleDOI
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.
Julia Wendon,Juan Córdoba,Anil Dhawan,Fin Stolze Larsen,Michael Manns,Frederik Nevens,Didier Samuel,Kenneth J. Simpson,Ilan Yaron,Mauro Bernardi +9 more
TL;DR: The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction, however, it refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease.
Journal ArticleDOI
Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial
Rafael Bañares,Rafael Bañares,Frederik Nevens,Fin Stolze Larsen,Rajiv Jalan,Agustín Albillos,Matthias M. Dollinger,Faouzi Saliba,Faouzi Saliba,Tilman Sauerbruch,Sebastian Klammt,Johann Ockenga,Albert Parés,Julia Wendon,Tanja Brünnler,Ludwig Kramer,Philippe Mathurin,Manuel de la Mata,Antonio Gasbarrini,Beat Müllhaupt,Alexander Wilmer,Wim Laleman,Martin Eefsen,Sambit Sen,Alexander Zipprich,Teresa Tenorio,Marco Pavesi,Hartmut Schmidt,Steffen Mitzner,Roger Williams,Vicente Arroyo +30 more
TL;DR: At scheduled doses, a beneficial effect on survival of MARS therapy in patients with ACLF could not be demonstrated, however, MARS has an acceptable safety profile, has significant dialysis effect, and nonsignificantly improves severe HE.
Journal ArticleDOI
High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial
Fin Stolze Larsen,Lars E. Schmidt,Christine Bernsmeier,Allan Rasmussen,Helena Isoniemi,Vishal C. Patel,Evangelos Triantafyllou,William Bernal,Georg Auzinger,Debbie L. Shawcross,Martin Eefsen,Peter Nissen Bjerring,Jens Otto Clemmesen,Krister Höckerstedt,Hans-Jørgen Frederiksen,Bent Adel Hansen,Charalambos G. Antoniades,Julia Wendon +17 more
TL;DR: Treatment with HVP improves outcome in patients with ALF by increasing liver transplantation-free survival by attributable to attenuation of innate immune activation and amelioration of multi-organ dysfunction.
Journal ArticleDOI
Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis
Tarek Hassanein,Flemming Tofteng,Robert S. Brown,Brendan M. McGuire,Patrick Lynch,Ravindra L. Mehta,Fin Stolze Larsen,Jeff Gornbein,Jan Stange,Andres T. Blei +9 more
TL;DR: The use of ECAD may be associated with an earlier and more frequent improvement of HE (grade 3/4) and a full assessment of the role of albumin dialysis awaits the results of additional controlled trials.