F
Frank Kunst
Researcher at Pasteur Institute
Publications - 60
Citations - 9582
Frank Kunst is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Bacillus subtilis & Genome. The author has an hindex of 42, co-authored 60 publications receiving 9144 citations. Previous affiliations of Frank Kunst include Centre national de la recherche scientifique.
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Genome Microevolution of Chikungunya Viruses Causing the Indian Ocean Outbreak
Isabelle Schuffenecker,Isabelle Iteman,Alain Michault,Séverine Murri,Lionel Frangeul,Marie-Christine Vaney,Marie-Christine Vaney,Rachel Lavenir,Nathalie Pardigon,Jean-Marc Reynes,François Pettinelli,Leon Biscornet,Laure Diancourt,Stéphanie Michel,Stéphane Duquerroy,Stéphane Duquerroy,Stéphane Duquerroy,Ghislaine Guigon,Marie-Pascale Frenkiel,Anne-Claire Brehin,Nadège Cubito,Philippe Desprès,Frank Kunst,Félix A. Rey,Félix A. Rey,Hervé Zeller,Sylvain Brisse +26 more
TL;DR: The results indicate that the chikungunya virus outbreak was initiated by a strain related to East-African isolates, from which viral variants have evolved following a traceable microevolution history and may be due to adaptation to the mosquito vector.
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Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity.
Christel Cazalet,Christophe Rusniok,Holger Brüggemann,Nora Zidane,Arnaud Magnier,Laurence Ma,Magalie Tichit,Sophie Jarraud,Christiane Bouchier,François Vandenesch,Frank Kunst,Jerome Etienne,Philippe Glaser,Carmen Buchrieser +13 more
TL;DR: The genome reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae, and encode eukaryotic-like proteins or motifs that are predicted to modulate host cell functions to the pathogen's advantage.
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The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens
Eric Duchaud,Christophe Rusniok,Lionel Frangeul,Carmen Buchrieser,Alain Givaudan,Sead Taourit,Stéphanie Bocs,Caroline Boursaux-Eude,Michael Chandler,Jean-François Charles,Elie Dassa,Richard Derose,Sylviane Derzelle,Georges Freyssinet,Sophie Gaudriault,Claudine Médigue,Anne Lanois,Kerrie Powell,Patricia Siguier,Rachel Vincent,Vincent Paul Mary Wingate,Mohamed Zouine,Philippe Glaser,Noël Boemare,Antoine Danchin,Frank Kunst +25 more
TL;DR: Compared with the genomes of related bacteria, the complete genome sequence of strain TT01 reveals the acquisition of virulence factors by extensive horizontal transfer and provides clues about the evolution of an insect pathogen.
Journal ArticleDOI
Multilocus Sequence Typing System for Group B Streptococcus
Nicola Jones,John F. Bohnsack,Shinji Takahashi,Karen A. Oliver,Man Suen Chan,Frank Kunst,Philippe Glaser,Christophe Rusniok,Derrick W. Crook,Rosalind M. Harding,Naiel Bisharat,Brian G. Spratt +11 more
TL;DR: The GBS MLST system offers investigators a valuable typing tool that will promote further investigation of the population biology of this organism and suggests that recombination occurs at the capsular locus.
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Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease.
Philippe Glaser,Christophe Rusniok,Carmen Buchrieser,Fabien Le Chevalier,Lionel Frangeul,Tarek Msadek,Mohamed Zouine,Elisabeth Couvé,Lila Lalioui,Claire Poyart,Patrick Trieu-Cuot,Frank Kunst +11 more
TL;DR: Compared with other pathogenic streptococci, S. agalactiae shows the unique feature that pathogenicity islands may have an important role in virulence acquisition and in genetic diversity.