F
Franz Fazekas
Researcher at Medical University of Graz
Publications - 634
Citations - 59050
Franz Fazekas is an academic researcher from Medical University of Graz. The author has contributed to research in topics: Hyperintensity & Stroke. The author has an hindex of 101, co-authored 629 publications receiving 49775 citations. Previous affiliations of Franz Fazekas include Hospital of the University of Pennsylvania & University of Graz.
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Journal ArticleDOI
Magnetization Transfer Ratio Relates to Cognitive Impairment in Normal Elderly
Stephan Seiler,Lukas Pirpamer,Edith Hofer,Marco Duering,Eric Jouvent,Franz Fazekas,Jean-François Mangin,Hugues Chabriat,Martin Dichgans,Stefan Ropele,Reinhold Schmidt +10 more
TL;DR: Approximate mixed models determined whole brain and lobar cortical MTR to be directly and significantly related to performance on tests of memory, executive function, and motor skills and to be independent of demographics, vascular risk factors, focal brain lesions, and cortex volume.
Journal ArticleDOI
Hyperinsulinaemia in migraineurs is associated with nitric oxide stress
Hans-Jürgen Gruber,Claudia Bernecker,Sabine Pailer,Günter Fauler,Renate Horejsi,Reinhard Möller,Anita Lechner,Franz Fazekas,M. Truschnig-Wilders +8 more
TL;DR: It is shown here that hyperinsulinaemia is associated with migraine and, furthermore, is correlated with increased NO stress, a new pathophysiological mechanism that may be of clinical relevance.
Journal ArticleDOI
GLP-2 and leptin are associated with hyperinsulinemia in non-obese female migraineurs.
Claudia Bernecker,Sabine Pailer,Petra Kieslinger,Renate Horejsi,Reinhard Möller,Anita Lechner,M Wallner-Blazek,Sabine Weiss,Franz Fazekas,M. Truschnig-Wilders,Hans-Jürgen Gruber +10 more
TL;DR: The data suggest that migraine is associated with a higher risk for insulin resistance and its clinical consequences, and it is shown that non-obese female migraineurs suffer from hyperinsulinemia, which isassociated with elevated leptin and GLP-2 levels.
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Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients
Harald Hegen,Indra Adrianto,Christopher J. Lessard,Alban Millonig,Antonio Bertolotto,Manuel Comabella,Gavin Giovannoni,Michael Guger,Martina Hoelzl,Michael Khalil,Franz Fazekas,Joep Killestein,Raija L.P. Lindberg,Simona Malucchi,Matthias Mehling,Xavier Montalban,Dagmar Rudzki,Franz Schautzer,Finn Sellebjerg,Per Soelberg Sørensen,Florian Deisenhammer,Lawrence Steinman,Robert C. Axtell +22 more
TL;DR: There is heterogeneity in the immunologic pathways of the RRMS population, which correlates with IFN-β response, and two subsets, associated with a good response to therapy, showed a significant reduction in relapse rates and no worsening of disability.
Journal ArticleDOI
Treatment effects of monthly intravenous immunoglobulin on patients with relapsing - remitting Multiple Sclerosis: Further analyses of the Austrian immunoglobulin in MS Study
TL;DR: The observation of clinical improvement in the early phase of IVIg medication may suggest the activation of repair mechanisms such as the promotion of remyelination while immunoregulatory effects would be expected as the cause of fewer exacerbations throughout the AIMS study.