F
Franz Fazekas
Researcher at Medical University of Graz
Publications - 634
Citations - 59050
Franz Fazekas is an academic researcher from Medical University of Graz. The author has contributed to research in topics: Hyperintensity & Stroke. The author has an hindex of 101, co-authored 629 publications receiving 49775 citations. Previous affiliations of Franz Fazekas include Hospital of the University of Pennsylvania & University of Graz.
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Journal ArticleDOI
Determinants of brain iron in multiple sclerosis: a quantitative 3T MRI study.
Michael Khalil,Christian Langkammer,Stefan Ropele,K. Petrovic,M Wallner-Blazek,Marisa Loitfelder,Margit Jehna,Gerhard Bachmaier,R. Schmidt,Christian Enzinger,S Fuchs,Franz Fazekas +11 more
TL;DR: Basal ganglia R2* levels were significantly increased in MS compared to CIS and healthy controls and the absence of increased iron levels in patients with CIS indicates that iron accumulation does not precede the development of MS.
Journal ArticleDOI
Physical Activity Prevents Progression for Cognitive Impairment and Vascular Dementia Results From the LADIS (Leukoaraiosis and Disability) Study
Ana Verdelho,Sofia Madureira,José M. Ferro,H. Baezner,Christian Blahak,Anna Poggesi,Michael G. Hennerici,Leonardo Pantoni,Franz Fazekas,Philip Scheltens,Gunhild Waldemar,Anders Wallin,Timo Erkinjuntti,Domenico Inzitari +13 more
TL;DR: Physical activity reduces the risk of cognitive impairment, mainly vascular dementia, in older people living independently, in elderly people with white matter changes living independently.
Journal ArticleDOI
R2* mapping for brain iron: associations with cognition in normal aging
C. Ghadery,Lukas Pirpamer,Edith Hofer,Christian Langkammer,Katja Petrovic,Marisa Loitfelder,Petra Schwingenschuh,Stephan Seiler,Marco Duering,Eric Jouvent,Helena Schmidt,Franz Fazekas,Jean-François Mangin,Hugues Chabriat,Martin Dichgans,Stefan Ropele,Reinhold Schmidt +16 more
TL;DR: It is concluded that higher R2*-determined iron in the basal ganglia correlates with cognitive impairment during brain aging independent of concomitant brain abnormalities.
Journal ArticleDOI
Accelerated evolution of brain atrophy and "black holes" in MS patients with APOE-epsilon 4.
Christian Enzinger,Stefan Ropele,Stephen M. Smith,S. Strasser-Fuchs,Birgit Poltrum,Helena Schmidt,Paul M. Matthews,Franz Fazekas +7 more
TL;DR: Accelerated brain tissue loss and a higher proportion of lesions evolving into BH therefore provide magnetic resonance imaging evidence for more pronounced tissue destruction in MS patients with APOE‐ε4.
Journal ArticleDOI
Quantitative assessment of brain iron by R(2)* relaxometry in patients with clinically isolated syndrome and relapsing-remitting multiple sclerosis.
Michael Khalil,Christian Enzinger,Christian Langkammer,M Tscherner,M Wallner-Blazek,Margit Jehna,Stefan Ropele,S Fuchs,Franz Fazekas +8 more
TL;DR: Quantitative assessment by R2* relaxometry suggests increased iron deposition in the basal ganglia of MS patients, which is associated with disease duration and brain atrophy.