F
Franz Oesch
Researcher at University of Mainz
Publications - 580
Citations - 22320
Franz Oesch is an academic researcher from University of Mainz. The author has contributed to research in topics: Epoxide hydrolase & Microsomal epoxide hydrolase. The author has an hindex of 76, co-authored 578 publications receiving 21684 citations. Previous affiliations of Franz Oesch include University of Basel & National Institutes of Health.
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Journal ArticleDOI
Genotoxicity of methyl acrylate and ethyl acrylate and its relationship with glutathione
Franz Oesch,Naveed Honarvar,Eric Fabian,Lavorgie Finch,Samantha Hindle Hindle,Karin Wiench,Robert Landsiedel +6 more
TL;DR: In this paper , the authors investigated whether the addition of glutathione to the in vitro L5178Y/TK +/− mouse lymphoma mutagenicity test prevents alkyl acrylate's mutagicity in vitro.
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Radioactively labelled epoxides. Part VI. tritium-labelled mono- and dimethyl substituted phenyl oxiranes (styrene oxides)
TL;DR: Tritium-labeled oxiranes were successfully used as diagnostic substrates to distinguish between different forms of epoxide hydrolase and glutathione transferase as mentioned in this paper.
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P-2-32 Action of reboxetine on selective drug metabolizing enzymes in rat liver
F. Fiorentini,Franz Oesch,Michael Arand,M. G. Castelli,Philippe Dostert,M. Strolin Benedetti +5 more
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32P-Postlabelling/HPLC Analysis of DNA Adducts Formed from Chrysene and its Metabolites
TL;DR: Metabolic activation of chrysene and three metabolites by aroclor-induced rat-liver homo-genate in the presence of calf-thymus DNA or in vivo following topical application to mouse skin yielded similar adduct patterns upon 32P-postlabelling/TLC analysis.