F
Franz Oesch
Researcher at University of Mainz
Publications - 580
Citations - 22320
Franz Oesch is an academic researcher from University of Mainz. The author has contributed to research in topics: Epoxide hydrolase & Microsomal epoxide hydrolase. The author has an hindex of 76, co-authored 578 publications receiving 21684 citations. Previous affiliations of Franz Oesch include University of Basel & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Distribution and induction of aflatoxin B1-9a-hydroxylase activity in rat liver parenchymal and non-parenchymal cells
TL;DR: The results suggest that the AFB1-9a-hydroxylase activity might be particularly important in NPC to protect these cells from AFB1 by converting it to a significantly less mutagenic metabolite and by reducing the amount of AFB1 available for epoxidation.
Journal ArticleDOI
Die Aktivierung der C‐2‐Position von Purin durch die Trifluormethansulfonatgruppe: Synthese von N2‐alkylierten Desoxyguanosinen
Journal ArticleDOI
A highly sensitive assay for epoxide hydrolase using an endogenous epoxide as substrate: 16α, 17α-epoxyandrost-4-en-3-one
TL;DR: This assay is widely applicable and valuable for the determination of epoxide hydrolase activity in tissue samples of low mass or low activity, since it uses an endogenous substrate of the enzyme.
Journal ArticleDOI
Synthesis of Stereoisomeric N 6-Deoxyadenosine Adducts of syn- and anti- Dihydrodiol Epoxides of Benzo[a]pyrene and Their Incorporation into 18-mer DNA Sequences from Human Ha-ras Protooncogene
TL;DR: This work reports the successful incorporation of trans-N 6-dA-B[a]PDE adducts derived from the syn- and anti-diastereomers of B[a]-PDE into 18-mer oligonucleotides representing partial human Ha-ras sequences surrounding codon 61 (CAG).