F
Franz Oesch
Researcher at University of Mainz
Publications - 580
Citations - 22320
Franz Oesch is an academic researcher from University of Mainz. The author has contributed to research in topics: Epoxide hydrolase & Microsomal epoxide hydrolase. The author has an hindex of 76, co-authored 578 publications receiving 21684 citations. Previous affiliations of Franz Oesch include University of Basel & National Institutes of Health.
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Density-dependent regulation of cell growth by contactinhibin and the contactinhibin receptor
TL;DR: Evidence is provided that a 92 kD plasma membrane protein, which is called CiR, binds specifically to contactinhibin and acts as a receptor mediating the contact-dependent inhibition of growth of cultured human fibroblasts, and that homeostasis is the net result of a highly balanced network of growth-stimulating and growth-inhibitory signals.
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The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases
Thomas Efferth,Franz Oesch +1 more
TL;DR: Artemisinin this article is a sesquiterpene lactone Artemisia annua L. It is well established for malaria therapy, but its bioactivity spectrum is much broader.
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Properties and amino acid composition of pure epoxide hydratase.
TL;DR: The results of initial investigations with the pure enzyme suggest that the properties of epoxide hydratase may contribute towards an understanding of the mechanisms of cytotoxicity and carcinogenesis.
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Concomitant induction of cytosolic but not microsomal epoxide hydrolase with peroxisomal β-oxidation by various hypolipidemic compounds
Ludwig Schladt,Renate Hartmann,Christopher Timms,M. Strolin-benedetti,P Dostert,Walter Wörner,Franz Oesch +6 more
TL;DR: The absence of an enhancement of cEH activity in in vitro studies confirmed that the increase in enzyme activity by the test compounds is not caused by activation.
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Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology.
Thomas Efferth,Franz Oesch +1 more
TL;DR: The present survey of the published literature clearly demonstrates that plant alkaloids have the potential for repositioning in cancer therapy.