F
Franziska Hufsky
Researcher at University of Jena
Publications - 33
Citations - 1100
Franziska Hufsky is an academic researcher from University of Jena. The author has contributed to research in topics: Medicine & String (computer science). The author has an hindex of 16, co-authored 30 publications receiving 859 citations. Previous affiliations of Franziska Hufsky include Max Planck Society & Schiller International University.
Papers
More filters
Journal ArticleDOI
Computational mass spectrometry for small molecules
TL;DR: This review covering the computational aspects of identifying small molecules, from the identification of a compound searching a reference spectral library, to the structural elucidation of unknowns, describes the basic principles and pitfalls of searching mass spectral reference libraries.
Journal ArticleDOI
Significance estimation for large scale metabolomics annotations by spectral matching
Kerstin Scheubert,Franziska Hufsky,Daniel Petras,Mingxun Wang,Louis-Félix Nothias,Kai Dührkop,Nuno A. G. Bandeira,Pieter C. Dorrestein,Sebastian Böcker +8 more
TL;DR: The authors develop strategies to estimate false discovery rates (FDR) by empirical Bayes and target-decoy based methods which enable a user to define the scoring criteria for spectral matching.
Journal ArticleDOI
Identifying the unknowns by aligning fragmentation trees
Florian Rasche,Kerstin Scheubert,Franziska Hufsky,Thomas Zichner,Marco Kai,Aleš Svatoš,Sebastian Böcker +6 more
TL;DR: This work presents a tool for searching a database for compounds with fragmentation pattern similar to an unknown sample compound, and applies this tool to metabolites from Icelandic poppy.
Journal ArticleDOI
Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research.
Franziska Hufsky,Kevin Lamkiewicz,Alexandre Almeida,Abdel Aouacheria,Cecilia N. Arighi,Alex Bateman,Jan Baumbach,Niko Beerenwinkel,Christian Brandt,Marco Cacciabue,Sara Chuguransky,Oliver Drechsel,Robert D. Finn,Adrian Fritz,Stephan Fuchs,Georges Hattab,Anne-Christin Hauschild,Dominik Heider,Marie Hoffmann,Martin Hölzer,Stefan Hoops,Lars Kaderali,Ioanna Kalvari,Max von Kleist,Renó Kmiecinski,Denise Kühnert,Gorka Lasso,Pieter Libin,Markus List,Hannah F. Löchel,Maria Jesus Martin,Roman Martin,Julian Matschinske,Alice C. McHardy,Pedro Mendes,Jaina Mistry,Vincent Navratil,Eric P. Nawrocki,Áine O'Toole,Nancy Ontiveros-Palacios,Anton I. Petrov,Guillermo Rangel-Pineros,Nicole Redaschi,Susanne Reimering,Knut Reinert,Alejandro Reyes,Lorna Richardson,David Robertson,Sepideh Sadegh,Joshua B Singer,Kristof Theys,Chris Upton,Marius Welzel,Lowri Williams,Manja Marz +54 more
TL;DR: Bioinformatics workflows and tools for the routine detection of SARS-CoV-2 infection, the reliable analysis of sequencing data, the tracking of the COVID-19 pandemic and evaluation of containment measures, the study of coronavirus evolution, the discovery of potential drug targets and development of therapeutic strategies are reviewed.
Journal ArticleDOI
Computational mass spectrometry for small-molecule fragmentation
TL;DR: In this article, the identification of small molecules from mass spectrometry (MS) data remains a major challenge in the interpretation of MS data, and computational aspects of identifying small molecules range from searching a reference spectral library to the structural elucidation of an unknown.