G
Gary A. Silverman
Researcher at Washington University in St. Louis
Publications - 139
Citations - 13136
Gary A. Silverman is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Serpin & Gene. The author has an hindex of 41, co-authored 131 publications receiving 12186 citations. Previous affiliations of Gary A. Silverman include University of Pittsburgh & Washington & Jefferson College.
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Journal ArticleDOI
Integration of 28 STSs into the physical map of human chromosome 18
Steve Gerken,Kimberlee E. Fish,Denise Uyar,Mihael H. Polymeropoulos,Paige Bradley,Ray White,Joan Overhauser,Gary A. Silverman +7 more
TL;DR: The purpose of this study was to integrate 9 new transcriptional tags [8 brain ESTs and the melanocortin 4 receptor (MC4R) (3)] and 19 simple sequence repeats (SSRs) into the physical map of human chromosome 18.
Posted ContentDOI
Quantitative Assessment Of Cell Fate Decision Between Autophagy And Apoptosis
Bing Liu,Zoltán N. Oltvai,Hülya Bayır,Gary A. Silverman,Stephen C. Pak,David H. Perlmutter,Ivet Bahar +6 more
TL;DR: A computational model of coupled apoptosis and autophagy is built here to study the systems-level dynamics of the underlying signaling network and identified Ca2+/calmodulin-dependent kinase kinase β (CaMKKβ) as a determinant of the opposite roles of cytoplasmic Ca2+.
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Integration of the 1993-94 genethon genetic linkage map for chromosome 18 with the physical map using a somatic cell hybrid mapping panel
TL;DR: There have been concerted efforts in the past 5 years to create a high-resolution genetic map for all of the human chromosomes that contain markers that can be analyzed using the polymerase chain reaction technique, but most published genetic maps contain minimal information about the physical location of the markers.
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Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants
June Y. Hu,Ping Yang,Daniel J. Wegner,Hillary B. Heins,Cliff J. Luke,Fuhai Li,Frances V. White,Gary A. Silverman,F. Sessions Cole,Jennifer A. Wambach +9 more
TL;DR: Qualitative and quantitative functional characterization of ABCA3 variants informs mechanisms of pathogenicity and suggests two pathogenic classes: disrupted intracellular trafficking and impaired ATPase‐mediated phospholipid transport into the lamellar bodies
Journal ArticleDOI
SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation
Songyan Wang,Cliff J. Luke,Stephen C. Pak,Victoria Shi,Liyun Chen,J. Russell Moore,Arlise P. Andress,Kay Jayachandran,Jin Zhang,Yi Huang,Marina Platik,A.A. Apicelli,Julie K. Schwarz,Perry W. Grigsby,Gary A. Silverman,Stephanie Markovina +15 more
TL;DR: The endogenous lysosomal cysteine protease inhibitor SERPINB3 (squamous cell carcinoma antigen 1, SCCA1) is elevated in patients with cervical cancer and other malignancies as discussed by the authors .