Gary J. Sarkis

TL;DR: A scalable, highly parallel sequencing system with raw throughput significantly greater than that of state-of-the-art capillary electrophoresis instruments with 96% coverage at 99.96% accuracy in one run of the machine is described.

TL;DR: In this paper, a method for nucleic acid amplification is described, in which the templates, beads, and amplification reaction solution are emulsified and the nucleic acids are amplified to provide clonal copies of the templates attached to the beads.

TL;DR: Of the amplification methodologies examined in this paper, the multiple displacement amplification products generated the least bias, and produced significantly higher yields of amplified DNA.

TL;DR: The PicoTiterPlate as discussed by the authors is a platform for simultaneous polymerase chain reaction (PCR) amplification of up to 300,000 discrete reactions in a novel platform, which can be performed in extremely small volumes: individual reactions volumes are as low as 39.5 pL, with a total 15.3 micro-L reaction volume for the entire platform.

TL;DR: In this article, the authors proposed a method of preparing a target nucleic acid fragments to produce a smaller nucleic acids which comprises the two ends of the target nucleIC acid.