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Jorge Galvez

Researcher at University of Valencia

Publications -  140
Citations -  3958

Jorge Galvez is an academic researcher from University of Valencia. The author has contributed to research in topics: Quantitative structure–activity relationship & Drug discovery. The author has an hindex of 29, co-authored 135 publications receiving 3600 citations. Previous affiliations of Jorge Galvez include Universidad Miguel Hernández de Elche & Polytechnic University of Valencia.

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Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study

Belén Gutiérrez-Gutiérrez, +93 more
TL;DR: Patients with BSIs due to CPE should receive active therapy as soon as they are diagnosed, and monotherapy should be considered for those in the low-mortality-score stratum.
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Computational Methods in Developing Quantitative Structure-Activity Relationships (QSAR): A Review

TL;DR: This review focuses on the methodologies in constructing three main components of QSAR model, namely the methods for describing the molecular structure of compounds, for selection of informative descriptors and for activity prediction.
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Charge Indexes. New Topological Descriptors

TL;DR: New topological descriptors, namely “charge indexes”, are presented and it is clearly demonstrated that their ability for the description of the molecular charge distribution is higher than that shown by the x connectivity and Wiener indexes.
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Some new trends in chemical graph theory.

TL;DR: Unidad de Investigación de Diseño de Farmacos y Conectividad Molecular, Departamento de Quisica Fisica, Facultad of Farmacı́a, Universitat de València, Spain, Instituto de Tecnologia Quimica, CSIC-Universidad Politecnica de Valencia,
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Topological approach to drug design.

TL;DR: It is demonstrated that by an adequate combination of different topological indices it is possible to select and design new active compounds in different therapeutical scopes, with a very high efficiency level.