G
Gerald F. Watts
Researcher at University of Western Australia
Publications - 961
Citations - 52245
Gerald F. Watts is an academic researcher from University of Western Australia. The author has contributed to research in topics: Lipoprotein & Apolipoprotein B. The author has an hindex of 100, co-authored 889 publications receiving 43807 citations. Previous affiliations of Gerald F. Watts include Glasgow Royal Infirmary & King's College London.
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Journal ArticleDOI
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society
Børge G. Nordestgaard,M. John Chapman,Steve E. Humphries,Henry N. Ginsberg,Luis Masana,Olivier S. Descamps,Olov Wiklund,Robert A. Hegele,Frederick J. Raal,Joep C. Defesche,Albert Wiegman,Raul D. Santos,Gerald F. Watts,Klaus G. Parhofer,G. Kees Hovingh,Petri T. Kovanen,Catherine Boileau,Maurizio Averna,Jan Borén,Eric Bruckert,Alberico L. Catapano,Jan Albert Kuivenhoven,Jan Albert Kuivenhoven,P. Pajukanta,Kausik K. Ray,Anton F. H. Stalenhoef,Erik S.G. Stroes,Marja-Riitta Taskinen,Anne Tybjærg-Hansen +28 more
TL;DR: There is an urgent worldwide need for diagnostic screening together with early and aggressive treatment of this extremely high-risk condition, familial hypercholesterolaemia.
Journal ArticleDOI
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
Brian A. Ference,Henry N. Ginsberg,Ian D. Graham,Kausik K. Ray,Chris J. Packard,Eric Bruckert,Robert A. Hegele,Ronald M. Krauss,Frederick J. Raal,Heribert Schunkert,Gerald F. Watts,Jan Borén,Sergio Fazio,Jay D. Horton,Luis Masana,Stephen J. Nicholls,Børge G. Nordestgaard,Børge G. Nordestgaard,Bart van de Sluis,Marja-Riitta Taskinen,Lale Tokgozoglu,Ulf Landmesser,Ulf Landmesser,Ulf Landmesser,Ulrich Laufs,Olov Wiklund,Olov Wiklund,Jane K Stock,M. John Chapman,Alberico L. Catapano +29 more
TL;DR: Consistent evidence from numerous and multiple different types of clinical and genetic studies unequivocally establishes that LDL causes ASCVD.
Journal ArticleDOI
Lipoprotein(a) as a cardiovascular risk factor: current status
Børge G. Nordestgaard,M. John Chapman,Kausik K. Ray,Jan Borén,Felicita Andreotti,Gerald F. Watts,Henry N. Ginsberg,Pierre Amarenco,Alberico L. Catapano,Olivier S. Descamps,Edward A. Fisher,Petri T. Kovanen,Jan Albert Kuivenhoven,Philippe Lesnik,Luis Masana,Zeljko Reiner,Marja-Riitta Taskinen,Lale Tokgozoglu,Anne Tybjærg-Hansen +18 more
TL;DR: The robust and specific association between elevated Lp(a) levels and increased cardiovascular disease (CVD)/coronary heart disease (CHD) risk, together with recent genetic findings, indicates that elevated LP(a), like elevated LDL-cholesterol, is causally related to premature CVD/CHD.
Journal ArticleDOI
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
M. John Chapman,Henry N. Ginsberg,Pierre Amarenco,Felicita Andreotti,Jan Borén,Alberico L. Catapano,Olivier S. Descamps,Edward A. Fisher,Petri T. Kovanen,Jan Albert Kuivenhoven,Philippe Lesnik,Luis Masana,Børge G. Nordestgaard,Kausik K. Ray,Zeljko Reiner,Marja-Riitta Taskinen,Lale Tokgozoglu,Anne Tybjærg-Hansen,Gerald F. Watts +18 more
TL;DR: Recommendations will facilitate reduction in the substantial cardiovascular risk that persists in patients with cardiometabolic abnormalities at LDL-C goal, and that therapeutic targeting of elevated triglycerides, a marker of TRL and their remnants, and/or low HDL-C may provide further benefit.
Journal ArticleDOI
Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production
Eric Boilard,Peter A. Nigrovic,Peter A. Nigrovic,Katherine Larabee,Gerald F. Watts,Jonathan S. Coblyn,Michael E. Weinblatt,Elena Massarotti,Eileen Remold-O'Donnell,Richard W. Farndale,Jerry Ware,David M. Lee +11 more
TL;DR: A previously unappreciated role for platelets and their activation-induced microparticles in inflammatory joint diseases is demonstrated and the collagen receptor glycoprotein VI is identified as a key trigger for platelet microparticle generation in arthritis pathophysiology.