G
Germaine C. Verwoert
Researcher at Erasmus University Medical Center
Publications - 22
Citations - 2153
Germaine C. Verwoert is an academic researcher from Erasmus University Medical Center. The author has contributed to research in topics: Blood pressure & Rotterdam Study. The author has an hindex of 15, co-authored 22 publications receiving 1908 citations. Previous affiliations of Germaine C. Verwoert include Leiden University & Erasmus University Rotterdam.
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Journal ArticleDOI
Evaluation of Newer Risk Markers for Coronary Heart Disease Risk Classification: A Cohort Study
Maryam Kavousi,Suzette E. Elias-Smale,Joost H.W. Rutten,Maarten J.G. Leening,Rozemarijn Vliegenthart,Germaine C. Verwoert,Gabriel P. Krestin,Matthijs Oudkerk,Moniek P.M. de Maat,Frank W.G. Leebeek,Francesco U.S. Mattace-Raso,Jan Lindemans,Albert Hofman,Ewout W. Steyerberg,Aad van der Lugt,Anton H. van den Meiracker,Jacqueline C.M. Witteman +16 more
TL;DR: In this paper, the authors assess whether newer risk markers for CHD risk prediction and stratification improve Framingham risk score (FRS) predictions. And they find that coronary artery calcium (CAC) scores improved the accuracy of risk prediction.
Journal Article
Evaluation of Newer Risk Markers for Coronary Heart Disease Risk Classification
Maryam Kavousi,Suzette E. Elias-Smale,Joost H.W. Rutten,Maarten J.G. Leening,Rozemarijn Vliegenthart,Germaine C. Verwoert,Gabriel P. Krestin,Matthijs Oudkerk,Moniek P.M. de Maat,Frank W.G. Leebeek,Francesco U.S. Mattace-Raso,Jan Lindemans,Albert Hofman,Ewout W. Steyerberg,Aad van der Lugt,Anton H. van den Meiracker,Jacqueline C.M. Witteman +16 more
TL;DR: Improvements in FRS predictions were most statistically and clinically significant with the addition of CAC scores, and whether to use CAC score screening as a more routine test for risk prediction requires full consideration of the financial and clinical costs of performing versus not performing.
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Georg Ehret,Teresa Ferreira,Daniel I. Chasman,Anne U. Jackson,Ellen M. Schmidt,Toby Johnson,Gudmar Thorleifsson,Jian'an Luan,Louise A. Donnelly,Stavroula Kanoni,Ann-Kristin Petersen,Vasyl Pihurl,Rona J. Strawbridge,Dmitry Shungin,Maria Hughes,Osorio Meirelles,Marika Kaakinen,Nabila Bouatia-Naji,Kati Kristiansson,Sonia Shah,Marcus E. Kleber,Xiuqing Guo,Leo-Pekka Lyytikäinen,Cristiano Fava,Nidas Eriksson,Ilja M. Nolte,Patrik K. E. Magnusson,Elias Salfati,Loukianos S. Rallidis,Elizabeth Theusch,Andrew J. Smith,Lasse Folkersen,Kate Witkowska,Tune H. Pers,Roby Joehanes,Stuart K. Kim,Lazaros Lataniotis,Rick Jansen,Andrew D. Johnson,Helen R. Warren,Young Jin Kim,Wei Zhao,Ying Wu,Bamidele O. Tayo,Murielle Bochud,Devin Absher,Linda S. Adair,Najaf Amin,Dan E. Arkingl,Tomas Axelsson,Damian Baldassarre,Beverley Balkau,Stefania Bandinelli,Michael R. Barnes,Inês Barroso,Stephen Bevan,Joshua C. Bis,Gyda Bjornsdottir,Michael Boehnke,Eric Boerwinkle,Lori L. Bonnycastle,Dorret I. Boomsma,Stefan R. Bornstein,Morris Brown,Michel Burnier,Claudia P. Cabrera,John C. Chambers,I-Shou Chang,Ching-Yu Cheng,Peter S. Chines,Ren-Hua Chung,Francis S. Collins,John M. C. Connell,Angela Döring,Jean Dallongeville,John Danesh,Ulf de Faire,Graciela E. Delgado,Anna F. Dominiczak,Alex S. F. Doney,Fotios Drenos,Sarah Edkins,John D. Eicher,Roberto Elosua,Stefan Enroth,Jeanette Erdmann,Per Eriksson,Tõnu Esko,Evangelos Evangelou,Alun Evans,Tove Fai,Martin Farra,Janine F. Felixl,Jean Ferrières,Luigi Ferrucci,Myriam Fornage,Terrence Forrester,Nora Franceschinil,Oscar H. Franco,Anders Franco-Cereceda,Ross M. Fraser,Santhi K. Ganesh,He Gao,Karl Gertow,Francesco Gianfagna,Bruna Gigante,Franco Giulianini,Anuj Goe,Alison H. Goodall,Mark O. Goodarzi,Mathias Gorski,Jürgen Grässler,Christopher J. Groves,Vilmundur Gudnason,Ulf Gyllensten,Göran Hallmans,Anna-Liisa Hartikainen,Maija Hassinen,Aki S. Havulinna,Caroline Hayward,Serge Hercberg,Karl-Heinz Herzig,Andrew A. Hicks,Aroon D. Hingorani,Joel N. Hirschhorn,Albert Hofmanl,Jostein Holmen,Oddgeir L. Holmen,Jouke-Jan Hottenga,Phil Howard,Chao A. Hsiung,Steven C. Hunt,M. Arfan Ikram,Thomas Illig,Carlos Iribarren,Richard A. Jensen,Mika Kähönen,Hyun Min Kang,Sekar Kathiresan,Brendan J. Keating,Kay-Tee Khaw,Yun Kyoung Kim,Eric Kim,Mika Kivimäki,Norman Klopp,Genovefa Kolovou,Pirjo Komulainen,Jaspal S. Kooner,Gulum Kosova,Ronald M. Krauss,Diana Kuh,Zoltán Kutalik,Johanna Kuusisto,Kirsti Kvaløy,Timo A. Lakka,Nanette R. Lee,I-Te Lee,Wen-Jane Lee,Daniel Levy,Xiaohui Li,Kae-Woei Liang,Honghuang Lin,Li Lin,Jaana Lindström,Stéphane Lobbens,Satu Männistö,Gabriele Müller,Martina Müller-Nurasyid,François Mach,Hugh S. Markus,Eirini Marouli,Mark I. McCarthy,Colin A. McKenzie,Pierre Meneton,Cristina Menni,Andres Metspalu,Vladan Mijatovic,Leena Moilanen,May E. Montasser,Andrew D. Morris,Alanna C. Morrison,Antonella Mulas,Ramaiah Nagaraja,Narisu Narisu,Kjell Nikus,Christopher J. O'Donnell,Paul F. O'Reilly,Ken K. Ong,Fred Paccaud,Cameron D. Palmer,Afshin Parsa,Nancy L. Pedersen,Brenda W.J.H. Penninx,Markus Perola,Annette Peters,Neil Poulter,Peter P. Pramstaller,Bruce M. Psaty,Thomas Quertermous,Dabeeru C. Rao,Asif Rasheed,N. William Rayner,Frida Renström,Rainer Rettig,Kenneth Rice,Robert Roberts,Lynda M. Rose,Jacques E. Rossouw,Nilesh J. Samani,Serena Sanna,Jouko Saramies,Heribert Schunkert,Sylvain Sebert,Wayne H-H Sheu,Young-Ah Shin,Xueling Sim,Johannes H. Smit,Albert V. Smith,Maria X. Sosa,Tim D. Spector,Alena Stančáková,Alice Stanton,Kathleen Stirrups,Heather M. Stringham,Johan Sundström,Amy J. Swift,Ann-Christine Syvänen,E-Shyong Tai,Toshiko Tanaka,Kirill Tarasov,Alexander Teumer,Unnur Thorsteinsdottir,Martin D. Tobin,Elena Tremoli,André G. Uitterlinden,Matti Uusitupa,Ahmad Vaez,Dhananjay Vaidya,Cornelia M. van Duijn,Erik P A Van Iperen,Ramachandran S. Vasan,Germaine C. Verwoert,Jarmo Virtamo,Veronique Vitart,Benjamin F. Voight,Peter Vollenweider,Aline Wagner,Louise V. Wain,Nicholas J. Wareham,Hugh Watldns,Alan B. Weder,Harm-Jan Westra,Rainford J. Wilks,Tom Wilsgaard,James F. Wilson,Tien Yin Wong,Tsun-Po Yang,Jie Yao,Loic Yengo,Weihua Zhang,Jing Hua Zhao,Xiaofeng Zhu,Pascal Bovet,Richard S. Cooper,Karen L. Mohlke,Danish Saleheen,Jong-Young Lee,Paul Elliott,Hinco J. Gierman,Cristen J. Willer,Lude Franke,G. Kees Hovingh,Kent D. Taylor,George Dedoussis,Peter S. Sever,Andrew Wong,Lars Lind,Themistocles L. Assimes,Inger Njølstad,Peter Schwarz,Claudia Langenberg,Harold Snieder,Mark J. Caulfield,E. Melander,Markku Laakso,Juha Saltevo,Rainer Rauramaa,Jaakko Tuomilehto,Erik Ingelsson,Terho Lehtimäki,Kristian Hveem,Walter Palmas,Winfried März,Meena Kumar,Veikko Salomaa,Yii-Der Ida Chen,Jerome I. Rotter,Philippe Froguel,Marjo-Riitta Järvelin,Edward G. Lakatta,Kari Kuulasmaa,Paul W. Franks,Anders Hamsten,H-Erich Wichmann,Colin N. A. Palmer,Kari Stefansson,Paul M. Ridker,Ruth J. F. Loos,Aravinda Chalcravarti,Panos Deloukas,Andrew P. Morris,Christopher Newton-Cheh,Patricia B. Munroe +312 more
TL;DR: The 66-SNP blood pressure risk score was significantly associated with target organ damage in multiple tissues but with minor effects in the kidney, expanding current knowledge of blood pressure–related pathways and highlighting tissues beyond the classical renal system in blood pressure regulation.
Journal ArticleDOI
Orthostatic Hypotension and Risk of Cardiovascular Disease in Elderly People: The Rotterdam Study
Germaine C. Verwoert,Francesco U.S. Mattace-Raso,Albert Hofman,Jan Heeringa,Bruno H. Ch. Stricker,Monique M.B. Breteler,Jacqueline C. M. Witteman +6 more
TL;DR: To determine the prognostic role of orthostatic hypotension for cardiovascular disease (CVD) and all‐cause mortality in elderly people, a large number of elderly people with a history of CVD are surveyed.
Journal ArticleDOI
Arterial Stiffness and Cerebral Small Vessel Disease: The Rotterdam Scan Study
Mariëlle M.F. Poels,Keren Zaccai,Germaine C. Verwoert,Meike W. Vernooij,Albert Hofman,Aad van der Lugt,Jacqueline C.M. Witteman,Monique M.B. Breteler,Francesco U.S. Mattace-Raso,M. Arfan Ikram +9 more
TL;DR: Increased arterial stiffness is associated with a larger volume of white matter lesions, and in persons with uncontrolled hypertension, higher aPWV was significantly associated with larger white matter lesion volume.